Intracoronary brachytherapy, a promising treatment option for diabetic patients: Results from a European multicenter registry (RENO)

Détails

ID Serval
serval:BIB_8B767F3BE9D1
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Intracoronary brachytherapy, a promising treatment option for diabetic patients: Results from a European multicenter registry (RENO)
Périodique
Catheterization and Cardiovascular Interventions
Auteur(s)
Naber  C. K., Baumgart  D., Bonan  R., Wegscheider  K., Serruys  P. W., Colombo  A., Silber  S., Eeckhout  E., Eggebrecht  H., Erbel  R., Urban  P.
ISSN
1522-1946 (Print)
Statut éditorial
Publié
Date de publication
02/2004
Volume
61
Numéro
2
Pages
173-8
Notes
Comparative Study
Journal Article
Multicenter Study --- Old month value: Feb
Résumé
Despite advances in the interventional treatment of coronary disease, diabetics still have double the case fatality rate as nondiabetics. The purpose of this analysis from the Radiation in Europe With Novoste (RENO) registry was to assess the clinical and angiographic 6-month outcome of diabetic patients in comparison to nondiabetic patients after localized beta-radiation. A total of 1,098 patients (83.8% with in-stent restenosis) treated with the Novoste Beta-Cath system in Europe were enrolled in the RENO registry. Diabetes was, irrespective of the type of lesion treated, no significant risk factor for major adverse cardiac events or target vessel revascularization. Individuals with diabetes (n = 256) and without diabetes (n = 833) displayed no significant differences concerning clinical or angiographic endpoints. Vascular brachytherapy appears to be the first technique to even out the increased risk of diabetic patients undergoing percutaneous coronary interventions in the routine clinical setting. Thus, intracoronary brachytherapy represents a promising treatment option for diabetic patients.
Mots-clé
Brachytherapy/*methods Chi-Square Distribution Coronary Angiography Coronary Disease/*complications/*radiotherapy/therapy Coronary Restenosis/*prevention & control *Diabetes Complications Female Humans Logistic Models Male Middle Aged Prospective Studies Registries Statistics, Nonparametric Stents Treatment Outcome
Pubmed
Web of science
Création de la notice
28/01/2008 10:51
Dernière modification de la notice
20/08/2019 15:50
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