Rational approach in the management of Pseudomonas aeruginosa infections.

Détails

ID Serval
serval:BIB_89903939D2F8
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Rational approach in the management of Pseudomonas aeruginosa infections.
Périodique
Current opinion in infectious diseases
Auteur(s)
Bassetti M., Vena A., Russo A., Croxatto A., Calandra T., Guery B.
ISSN
1473-6527 (Electronic)
ISSN-L
0951-7375
Statut éditorial
Publié
Date de publication
12/2018
Peer-reviewed
Oui
Volume
31
Numéro
6
Pages
578-586
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
This review details the management of Pseudomonas aeruginosa infections covering both current and future treatment options that are and may be available for the clinicians.
Pseudomonas aeruginosa infections are a great concern in hospital-acquired infections with very limited therapeutic options. The increasing antibiotic resistance has led to a need for different treatment choices that range from the use of new antibiotics to new nonantibiotic alternative agents to kill or disarm the pathogen.
New molecules such as ceftolozane-tazobactam, ceftazidime-avibactam, and imipenem-relebactam have shown an adequate activity against P. aeruginosa, especially against multidrug resistance strains. Other nonantibiotic alternative treatments, such as antibodies, bacteriocins or phage therapy, have shown promising results, but future clinical studies are needed.
Mots-clé
Anti-Bacterial Agents/pharmacology, Anti-Bacterial Agents/therapeutic use, Bacteremia/drug therapy, Bacteremia/microbiology, Drug Resistance, Multiple, Bacterial, Humans, Pneumonia, Ventilator-Associated/drug therapy, Pneumonia, Ventilator-Associated/microbiology, Pseudomonas Infections/drug therapy, Pseudomonas Infections/microbiology, Pseudomonas aeruginosa/drug effects
Pubmed
Web of science
Création de la notice
17/10/2018 9:41
Dernière modification de la notice
26/10/2019 6:09
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