Cell cycle regulators in the control of metabolism.

Détails

ID Serval
serval:BIB_893BF44C6F6E
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Cell cycle regulators in the control of metabolism.
Périodique
Cell Cycle
Auteur⸱e⸱s
Blanchet E., Annicotte J.S., Fajas L.
ISSN
1551-4005 (Electronic)
ISSN-L
1551-4005
Statut éditorial
Publié
Date de publication
2009
Volume
8
Numéro
24
Pages
4029-4031
Langue
anglais
Résumé
We recently showed that the CDK4-pRB-E2F1 cell cycle regulators directly regulate the expression of Kir6.2, which is a key component of the K(ATP) channel involved in the regulation of glucose-induced insulin secretion. There is enough evidence to indicate that the CDK4-pRB-E2F1 regulatory pathway is involved in general glucose homeostasis, and metabolism. In this article we discuss which are the metabolic implications of these findings.
Mots-clé
Adipocytes/cytology, Adipocytes/metabolism, Animals, Blood Glucose/metabolism, Cell Cycle/physiology, Cyclin-Dependent Kinase 4/metabolism, E2F1 Transcription Factor/metabolism, Energy Metabolism/physiology, Homeostasis/physiology, Humans, Lipid Metabolism/physiology
Pubmed
Web of science
Création de la notice
07/03/2013 16:57
Dernière modification de la notice
20/08/2019 15:48
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