Anemia on admission predicts short- and long-term outcomes in patients with acute ischemic stroke.

Détails

ID Serval
serval:BIB_88BD8F56F47C
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Anemia on admission predicts short- and long-term outcomes in patients with acute ischemic stroke.
Périodique
International Journal of Stroke
Auteur⸱e⸱s
Milionis H., Papavasileiou V., Eskandari A., D'Ambrogio-Remillard S., Ntaios G., Michel P.
ISSN
1747-4949 (Electronic)
ISSN-L
1747-4930
Statut éditorial
Publié
Date de publication
2015
Peer-reviewed
Oui
Volume
10
Numéro
2
Pages
224-230
Langue
anglais
Notes
Publication types: Journal Article Publication Status: ppublish
Résumé
BACKGROUND: It is still debatable whether anemia predicts stroke outcome.
AIM: To describe the characteristics of patients with acute ischemic stroke (AIS) and anemia and identify whether hemoglobin status on admission is a prognostic factor of AIS outcome.
METHODS: All 2439 patients of the Acute Stroke Registry and Analysis of Lausanne (ASTRAL) between January 2003 and June 2011 were selected. Demographics, risk factors, prestroke treatment, clinical, radiological and metabolic variables in patients with and without anemia according to the definition of the World Health Organization were compared. Functional disability and mortality were recorded up to 12 months from admission.
RESULTS: Anemic patients (17.5%) were older, had lower body mass index, higher rates of coronary artery disease (CAD), atrial fibrillation, diabetes mellitus and peripheral artery disease. Anemia was associated with more severe stroke manifestations, lower systolic and diastolic blood pressure measurements, worse estimated glomerular filtration rate and elevated C-reactive protein concentrations upon admission and with increased modified Rankin scores during the follow-up. Anemic patients had higher 7-day, 3-month and 12-month mortality, which was associated with hemoglobin status and other factors, including age, CAD, stroke severity, and baseline C-reactive levels. Hemoglobin levels were inversely associated with recurrent stroke and mortality throughout the 12-month follow-up.
CONCLUSION: Anemia is common among AIS patients and is associated with cardiovascular comorbidities. Low hemoglobin status independently predicts short and long-term mortality.
Pubmed
Web of science
Création de la notice
06/03/2015 19:09
Dernière modification de la notice
20/08/2019 14:47
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