[Contents] P. 533-548: Assessing the effectiveness of integrated interventions: terminology and approach / Graeme Smith and David Clarke. P. 549-572: Epidemiologic trends and costs of fragmentation / Roger Kathol et al. P. 573-591: The metabolic syndrome, depression and cardiovascular disease : interrelated conditions that share pathophysiologic mechanisms / Rijk O.B. Gans. P. 593-601: Vulnerability in the elderly : frailty / Joris P.J. Slaets. P. 603-626: Symptoms, syndromes, and the value of psychiatric diagnosis in patients who have functional somatic disorders / Kurt Kroenke and Judith G.M. Rosmalen. P. 627-646: Disease-focused or integrated treatment : diabetes and depression / Leonard E. Egede. P. 647-677: Models of integrated care / Lawson R. Wulsin, Wolfgang Söllner, and Harold Alan Pincus. P. 679-692: Case and care complexity in the mentally ill / Peter de Jonge, Frits J. Huyse and Friedrich C. Stiefel. P. 693-701: The complexity of communication in an environment with multiple disciplines and professionals : communimetrics and decision support. P. 703-712: Identifiers, or "Red flags," of complexity and need for integrated care / Fritz J. Huyse, Friedrich C. Stiefel and Peter de Jonge. P. 713-758: Operationalizing integrated care on a clinical level : the INTERMED Project / Friedrich C. Stiefel, et al. P. 759-760: Reflections and perspectives / Friedrich C. Stiefel and Frits J. Huyse.