Commentary on the WHO classification of tumors of lymphoid tissues (2008): aggressive B-cell lymphomas.

Détails

ID Serval
serval:BIB_878FA06C0A02
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Commentary on the WHO classification of tumors of lymphoid tissues (2008): aggressive B-cell lymphomas.
Périodique
Journal of Hematopathology
Auteur(s)
Balague Ponz O., Ott G., Hasserjian R.P., Elenitoba-Johnson K.S., de Leval L., de Jong D.
ISSN
1865-5785[electronic]
Statut éditorial
Publié
Date de publication
2009
Peer-reviewed
Oui
Volume
2
Pages
83-87
Langue
anglais
Résumé
In the novel WHO classification 2008, the classification of aggressive B-cell lymphoma has been revised for several categories with the aim to define "clean" entities. Within large B-cell lymphoma, a few distinct clinico-pathological entities have been recognized with more clinically defined entities than pathologically defined ones. The majority of known morphological variations were not considered to merit more than classification as a variant of DLBCL, not otherwise specified. Specifically, a biological subgrouping of DLBCL on the basis of molecular (activated B-cell versus germinal center B-cell) or immunophenotypic (CD5+) features was felt to be too immature to include at this stage. The role of EBV in aggressive B-cell lymphoma has been explored in more depth with the recognition of several novel and re-defined clinico-pathological entities. Also, in these diseases, clinical definitions play a very dominant role in the WHO classification 2008.
Pubmed
Open Access
Oui
Création de la notice
22/10/2010 13:39
Dernière modification de la notice
20/08/2019 14:46
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