Neuroimaging of tic disorders with co-existing attention-deficit/hyperactivity disorder.

Détails

ID Serval
serval:BIB_8609D7925D4E
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Neuroimaging of tic disorders with co-existing attention-deficit/hyperactivity disorder.
Périodique
European child & adolescent psychiatry
Auteur(s)
Plessen K.J., Royal J.M., Peterson B.S.
ISSN
1018-8827 (Print)
ISSN-L
1018-8827
Statut éditorial
Publié
Date de publication
06/2007
Peer-reviewed
Oui
Volume
16 Suppl 1
Pages
60-70
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
Tourette syndrome (TS) and Attention-Deficit/Hyperactivity Disorder (ADHD) are common and debilitating neuropsychiatric illnesses that typically onset in the preschool years. Recently, both conditions have been subject to neuroimaging studies, with the aim of understanding their underlying neurobiological correlates.
The relation of TS and ADHD is discussed against the background of findings from previous Magnetic Resonance Imaging (MRI) studies.
We review the designs and major findings of previous studies that have examined TS with comorbid ADHD, and we briefly contrast these findings with those in ADHD without comorbid tic disorders.
The frequent comorbidity of TS and ADHD may reflect a common underlying neurobiological substrate, and studies confirm the hypothesized involvement of fronto-striatal circuits in both TS and ADHD. However, poor inhibitory control and volumetric reductions in fronto-striatal circuits appear to be core features of ADHD, whereas reduced volumes of the caudate nucleus, together with activation and hypertrophy of prefrontal regions that likely help to suppress tics, seem to be core features of TS.
The etiological relationship between TS and ADHD must be clarified further with cross-sectional and, if possible, longitudinal imaging studies that examine samples of substantial size, including subgroups with pure TS and ADHD, as well as with comorbid conditions.
Mots-clé
Adolescent, Attention Deficit Disorder with Hyperactivity/complications, Attention Deficit Disorder with Hyperactivity/diagnosis, Attention Deficit Disorder with Hyperactivity/pathology, Attention Deficit Disorder with Hyperactivity/physiopathology, Brain/pathology, Brain Mapping, Caudate Nucleus/pathology, Caudate Nucleus/physiopathology, Child, Corpus Callosum/pathology, Corpus Callosum/physiopathology, Corpus Striatum/pathology, Corpus Striatum/physiopathology, Dominance, Cerebral/physiology, Frontal Lobe/pathology, Frontal Lobe/physiopathology, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Nerve Net/pathology, Nerve Net/physiopathology, Neural Inhibition/physiology, Neuronal Plasticity/physiology, Prefrontal Cortex/pathology, Prefrontal Cortex/physiopathology, Reference Values, Tourette Syndrome/complications, Tourette Syndrome/diagnosis, Tourette Syndrome/pathology, Tourette Syndrome/physiopathology, gamma-Aminobutyric Acid/physiology
Pubmed
Web of science
Création de la notice
21/02/2019 10:17
Dernière modification de la notice
20/08/2019 14:45
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