Antiretrovirale Therapie [Antiretroviral therapy].

Détails

ID Serval
serval:BIB_84DE752C4AEF
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Antiretrovirale Therapie [Antiretroviral therapy].
Périodique
Therapeutische Umschau. Revue Thérapeutique
Auteur(s)
von Braun A., Furrer H., Battegay M., Calmy A., Cavassini M., Vernazza P., Bernasconi E., Weber R., Günthard H.F.
ISSN
0040-5930 (Print)
ISSN-L
0040-5930
Statut éditorial
Publié
Date de publication
2014
Peer-reviewed
Oui
Volume
71
Numéro
8
Pages
461-468
Langue
allemand
Notes
Publication types: English Abstract ; Journal Article ; Review Publication Status: ppublish
Résumé
Antiretroviral therapy to treat HIV, as we know it today, is nothing less than a huge success story in modern medical history. What used to be an almost certain death-sentence was transformed into a very manageable chronic disease by means of highly efficient und mostly well tolerated drugs. Today, HIV-infected patients treated according to international recommendations have a very good chance to outgo the negative effects of HIV-1 and are therefore able to reach an almost normal life expectancy. Furthermore, patients successfully treated with antiretroviral drugs are no longer infectious, which is an essential aspect of global strategies to overcome the pandemic. Nevertheless, due to the complexity of HIV, physicians treating patients with antiretroviral therapy require profound knowledge of aspects such as viral resistance mechanisms and immune reconstitution, as well as drug-toxicity und drug-drug-interactions. Many other aspects such as long-term side-effects of antiretroviral drugs are still unknown. Strict adherence to treatment is of utmost importance.
Mots-clé
Anti-HIV Agents/adverse effects, Anti-HIV Agents/therapeutic use, Cause of Death, Drug Interactions, Drug Resistance, Viral, Drug Therapy, Combination, Early Medical Intervention, Follow-Up Studies, Guideline Adherence, HIV Infections/diagnosis, HIV Infections/drug therapy, HIV-1/drug effects, Humans, Life Expectancy, hic" UI="D013557">Switzerland
Pubmed
Création de la notice
16/01/2015 11:53
Dernière modification de la notice
20/08/2019 14:44
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