Effect of dexfenfluramine on energy expenditure in man.
Détails
ID Serval
serval:BIB_8499CCA34429
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Effect of dexfenfluramine on energy expenditure in man.
Périodique
International Journal of Obesity and Related Metabolic Disorders
ISSN
0307-0565 (Print)
ISSN-L
0307-0565
Statut éditorial
Publié
Date de publication
1992
Volume
16 Suppl 3
Pages
S61-S66
Langue
anglais
Résumé
A short review has been made of the experimental studies performed in man, in which the effect of dexfenfluramine (D-F) on resting energy expenditure has been explored. It appears that the extent to which D-F possesses thermogenic properties (in addition to its anorectic effect) still remains controversial. Some investigators found either no significant increase in energy expenditure in response to the drug or a moderate effect in post-absorptive and/or postprandial state. It may be reasonable to assume that the supplementary weight loss observed with D-F as compared to a placebo can be primarily attributed to its anorectic effect rather than to its putative thermogenic effect.
Mots-clé
Adult, Basal Metabolism/drug effects, Body Temperature Regulation/drug effects, Energy Metabolism/drug effects, Female, Fenfluramine/pharmacology, Fenfluramine/therapeutic use, Humans, Male, Obesity/drug therapy, Obesity/metabolism
Pubmed
Web of science
Création de la notice
21/01/2008 14:07
Dernière modification de la notice
20/08/2019 15:44