Extraction of epileptogenic foci from PET and SPECT images by fuzzy modeling and data fusion

Détails

ID Serval
serval:BIB_83E5AEA7212C
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Extraction of epileptogenic foci from PET and SPECT images by fuzzy modeling and data fusion
Périodique
Neuroimage
Auteur⸱e⸱s
Boussion N., Cinotti L., Barra V., Ryvlin P., Mauguiere F.
ISSN
1053-8119 (Print)
ISSN-L
1053-8119
Statut éditorial
Publié
Date de publication
07/2003
Volume
19
Numéro
3
Pages
645-54
Langue
anglais
Notes
Boussion, N
Cinotti, L
Barra, V
Ryvlin, P
Mauguiere, F
eng
Clinical Trial
Neuroimage. 2003 Jul;19(3):645-54.
Résumé
During the presurgical evaluation of medically intractable epilepsy, isotopic functional imagery provides an increasing amount of data concerning the potential location of the focus. The aim of this study is to facilitate the surgical decision by presenting an image fusion method able to extract epileptogenic foci from periictal single photon emission computed tomography (SPECT), interictal SPECT, fluoro-desoxy-glucose (FDG) position emission tomography (PET), and flumazenil PET. After spatial coregistration, the images are converted into fuzzy maps whose membership functions indicate the pathological degree of each voxel, according to each modality. These maps are then fused together thanks to a combination operator managing uncertainty (due to the sensitivity) and imprecision (due to poor resolution and partial volume effect) of the images. In the framework of possibilistic theory, this operator mimics the way the physicians evaluate and compare the various exams. The technique was successfully tested on simulated images with well-defined abnormalities, in terms of size and intensity. A preliminary clinical study was also performed and gave results in accordance with the "gold standard" investigation (deep electrodes or postsurgical outcome) in 11 patients out of 12.
Mots-clé
Adult, Brain Mapping, Cerebral Cortex/*physiopathology, Cluster Analysis, Cognition/*physiology, Female, Hot Temperature, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Male, Pain/*physiopathology/*psychology, Psychomotor Performance/*physiology
Pubmed
Création de la notice
29/11/2018 13:36
Dernière modification de la notice
20/08/2019 15:43
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