Release of ethanolamine, but not of serine or choline, in rat pontine nuclei on stimulation of afferents from the cortex, in vivo.

Détails

ID Serval
serval:BIB_83E25CB82712
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Release of ethanolamine, but not of serine or choline, in rat pontine nuclei on stimulation of afferents from the cortex, in vivo.
Périodique
Journal of Neurochemistry
Auteur(s)
Perschak H., Wolfensberger M., Do K.Q., Dunant Y., Cuénod M.
ISSN
0022-3042 (Print)
ISSN-L
0022-3042
Statut éditorial
Publié
Date de publication
1986
Peer-reviewed
Oui
Volume
46
Numéro
5
Pages
1338-1343
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Résumé
Release of ethanolamine, serine, and choline in rat pontine nuclei on electrical stimulation of afferents from the cortex was investigated using in vivo push-pull cannula techniques. Ethanolamine was determined by using gas chromatographic techniques; serine was measured with a HPLC system; and choline was assayed with a luminescence method. Resting elution rates of ethanolamine, serine, and choline were 50.8 +/- 8.4, 34.8 +/- 12.6, and 1.16 +/- 0.20 pmol/5 min, respectively. Stimulation of the cortico-pontine tract evoked a highly significant 3.4-fold increase in release of ethanolamine, whereas serine and choline release was unaffected. Reactions in membrane phospholipids are most likely involved in the stimulation-dependent release of ethanolamine and special consideration was given to base-exchange reactions. Alternatively, a release from intracellular, possibly synaptic stores cannot be excluded.
Mots-clé
Afferent Pathways/physiology, Animals, Cerebral Cortex/physiology, Choline/metabolism, Electric Stimulation, Ethanolamine, Ethanolamines/metabolism, Female, Kinetics, Male, Mesencephalon/physiology, Pons/physiology, Rats, Rats, Inbred Strains, Serine/metabolism
Pubmed
Création de la notice
06/03/2014 17:03
Dernière modification de la notice
20/08/2019 15:43
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