Artificial Urinary Sphincter based on smart materials

Détails

ID Serval
serval:BIB_83903396C275
Type
Actes de conférence (partie): contribution originale à la littérature scientifique, publiée à l'occasion de conférences scientifiques, dans un ouvrage de compte-rendu (proceedings), ou dans l'édition spéciale d'un journal reconnu (conference proceedings).
Sous-type
Abstract (résumé de présentation): article court qui reprend les éléments essentiels présentés à l'occasion d'une conférence scientifique dans un poster ou lors d'une intervention orale.
Collection
Publications
Institution
Titre
Artificial Urinary Sphincter based on smart materials
Titre de la conférence
45th Congress of the European Society for Surgical Research
Auteur(s)
Valerio M., Tozzi P., Wieland M., Conus P-A., Thevenaz P., Mundy A. R., Hayoz D., Jichlinski P.
Adresse
Geneva - Switzerland, 9-12 June, 2010
ISBN
0007-1323
Statut éditorial
Publié
Date de publication
2010
Peer-reviewed
Oui
Volume
97
Série
British Journal of Surgery
Pages
S105
Langue
anglais
Notes
Meeting Abstract
Résumé
Objective:
There are only a few established artificial urinary sphincters for treatment of incontinence. We have developed a new device composed by three parts: the actuator, three contractile rings and a control unit. The actuator is made of Nitinol fibers, driven by microprocessor. The fibers are linked to the rings placed around the urethra. They function with alternance in their open and closed position. This concept is called piano concept. With this set-up, the constant compression on the urethra is strongly reduced.
Methods:
Six male sheep have been used for this study. The sphincter was open each hour for a period of 10 min., to guaranty urination. The bladder was filled with water while one cuff was closed and bladder pressure was monitored. The animals were sacrificed. Two biopsies around two cuffs of each explant and all three cuffs from each explant including urethra were analyzed. Urethra not surrounded by a cuff was taken as control.
Results:
The pressure exerted by the sphincter around the urethra provided continence. Simulated incontinence occurred at a pressure of 1bar measured on the bladder wall using a pressure probe. The closing force of the cuff was approx. 0·7N. No difference in tissue structure and organization of the urethra with and without artificial sphincter was observed.
Conclusions:
This device has several advantages compared to other urinary sphincters. It is easy to implant, has no hydraulic nature and reduces ischemic injury of the urethra by the alternance of urethral part compressed. Proof of concept in vivo has been demonstrated. Other studies are planned to determine long-term outcome.
Web of science
Création de la notice
21/10/2010 11:07
Dernière modification de la notice
20/08/2019 15:43
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