Treatment of autoinflammatory diseases: results from the Eurofever Registry and a literature review.

Détails

ID Serval
serval:BIB_82A5BAE9F71A
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Treatment of autoinflammatory diseases: results from the Eurofever Registry and a literature review.
Périodique
Annals of the rheumatic diseases
Auteur⸱e⸱s
Ter Haar N., Lachmann H., Özen S., Woo P., Uziel Y., Modesto C., Koné-Paut I., Cantarini L., Insalaco A., Neven B., Hofer M., Rigante D., Al-Mayouf S., Touitou I., Gallizzi R., Papadopoulou-Alataki E., Martino S., Kuemmerle-Deschner J., Obici L., Iagaru N., Simon A., Nielsen S., Martini A., Ruperto N., Gattorno M., Frenkel J.
Collaborateur⸱rice⸱s
Paediatric Rheumatology International Trials Organisation (PRINTO) and the Eurofever/Eurotraps Projects
Contributeur⸱rice⸱s
Kondi A., De Cunto C., Espada G., Russo R., Amaryan G., Boros C., Wouters C., de Oliveira S.K., Borzutzky A., Jelusic-Drazic M., Dolezalova P., Herlin T., Desjonqueres M., Djeddi D., Hentgen V., Darce M., Ioseliani M., Berendes R., Horneff G., Jansson A., Minden K., Schwarz T., Trauzeddel R., Kanakoudi Tsakalidou F., Vougiouka O., Constantin T., Rao A.P., Brik R., Harel L., Alessio M., Breda L., Cimaz R., Consolini R., Fabio G., Garozzo R., Lepore L., Manna R., Meini A., Olivieri A.N., Stanevicha V., Rusoniene S., Hoppenreijs E., Al-Abrawi Sy, Nikishina I., Sewairi W.M., Susic G., Ciznar P., Avcin T., Anton J., Bou R., Merino R., Elorduy M.J., Fasth A., Aksu G., Demirkaya E.
ISSN
1468-2060 (Electronic)
ISSN-L
0003-4967
Statut éditorial
Publié
Date de publication
05/2013
Peer-reviewed
Oui
Volume
72
Numéro
5
Pages
678-685
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Résumé
To evaluate the response to treatment of autoinflammatory diseases from an international registry and an up-to-date literature review.
The response to treatment was studied in a web-based registry in which clinical information on anonymised patients with autoinflammatory diseases was collected retrospectively as part of the Eurofever initiative. Participating hospitals included paediatric rheumatology centres of the Paediatric Rheumatology International Trial Organisation network and adult centres with a specific interest in autoinflammatory diseases. The following diseases were included: familial Mediterranean fever (FMF), cryopyrin-associated periodic syndromes (CAPS), tumour necrosis factor (TNF)-receptor associated periodic syndrome (TRAPS), mevalonate kinase deficiency (MKD), pyogenic arthritis pustulosis acne (PAPA) syndrome, deficiency of interleukin-1 receptor antagonist (DIRA), NLRP12-related periodic fever and periodic fever aphthosis pharyngitis adenitis (PFAPA) syndrome. Cases were independently validated by experts for each disease. A literature search regarding treatment of the abovementioned diseases was also performed using Medline and Embase.
22 months from the beginning of the enrolment, complete information on 496 validated patients was available. Data from the registry in combination with evidence from the literature confirmed that colchicine is the treatment of choice for FMF and IL-1 blockade for DIRA and CAPS. Corticosteroids on demand probably represent a valid therapeutic strategy for PFAPA, but also for MKD and TRAPS. Patients with poorly controlled MKD, TRAPS, PAPA or FMF may benefit from IL-1 blockade; anti-TNF treatment may represent a possible valuable alternative.
In the absence of high-grade evidence, these results could serve as a basis for therapeutic guidelines and to identify candidate drugs for future therapeutic trials.
Mots-clé
Acne Vulgaris/epidemiology, Acne Vulgaris/therapy, Arthritis, Infectious/epidemiology, Arthritis, Infectious/therapy, Cryopyrin-Associated Periodic Syndromes/epidemiology, Cryopyrin-Associated Periodic Syndromes/therapy, Europe/epidemiology, Familial Mediterranean Fever/epidemiology, Familial Mediterranean Fever/therapy, Humans, Mevalonate Kinase Deficiency/epidemiology, Mevalonate Kinase Deficiency/therapy, Pyoderma Gangrenosum/epidemiology, Pyoderma Gangrenosum/therapy, Registries/statistics & numerical data
Pubmed
Web of science
Création de la notice
03/05/2013 20:34
Dernière modification de la notice
03/05/2020 7:01
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