Pharmacological studies on meprobamate incorporation in human beard hair.
Détails
ID Serval
serval:BIB_8022DBB1FEB7
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Pharmacological studies on meprobamate incorporation in human beard hair.
Périodique
International Journal of Legal Medicine
ISSN
0937-9827[print], 0937-9827[linking]
Statut éditorial
Publié
Date de publication
1993
Volume
105
Numéro
5
Pages
283-287
Langue
anglais
Résumé
The time course of appearance of meprobamate in beard hair after single oral administration (400, 800, or 1200 mg) was monitored in 3 groups of 4 subjects by GC/MS. Meprobamate appeared in beard hair approximately 4-5 days after administration and peaked during the 7-9th day. Drug levels in beard hair appeared to be dose-related.
Mots-clé
Administration, Oral, Adult, Dose-Response Relationship, Drug, Gas Chromatography-Mass Spectrometry, Hair/metabolism, Humans, Male, Meprobamate/administration & dosage, Meprobamate/pharmacokinetics, Metabolic Clearance Rate/physiology
Pubmed
Création de la notice
18/10/2010 13:59
Dernière modification de la notice
20/08/2019 14:40