Brainstem Gliomas. A 10-year institutional review

Détails

ID Serval
serval:BIB_7F590325433D
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Brainstem Gliomas. A 10-year institutional review
Périodique
Pediatric Neurosurgery
Auteur(s)
Farmer  J. P., Montes  J. L., Freeman  C. R., Meagher-Villemure  K., Bond  M. C., O'Gorman  A. M.
ISSN
1016-2291 (Print)
Statut éditorial
Publié
Date de publication
2001
Volume
34
Numéro
4
Pages
206-214
Notes
PT - Case Reports PT - Clinical Trial PT - Journal Article PT - Multicenter Study
Résumé
Case records of 37 patients with a diagnosis of brainstem glioma treated at the Montreal Children's Hospital from June 1989 to June 1999 were reviewed. 15 patients had diffuse pontine gliomas and 22 patients had focal forms of brainstem gliomas. The two groups were compared with respect to age, clinical evolution, radiological appearance, type of surgery practised, histological diagnosis, adjuvant treatments and survival. A non-pontine brainstem location, a cystic or exophytic component, bright enhancement with gadolinium injection, a histological diagnosis of pilocytic astrocytoma or ganglioglioma were favourable prognostic factors. Progression-free survival and overall survival were significantly worse in the group of patients with diffuse pontine gliomas. The relative impact of radical surgery and/or radiotherapy is analysed. Surgery coupled to adjuncts such as navigation, ultrasound and monitoring plays an important role for focal brainstem lesions. Focal/conformal radiotherapy has an adjuvant role but better treatments are needed for the diffuse pontine brainstem lesions
Mots-clé
Adolescent/Brain Stem/Pathology/radiation effects/surgery/Child/Child,Preschool/Female/Follow-Up Studies/Gadolinium/diagnostic use/Glioma/radiotherapy/Humans/Magnetic Resonance Imaging/Male/Microsurgery/Monitoring,Intraoperative/Radiopharmaceuticals/Radiotherapy Dosage/Retrospective Studies/Time Factors
Pubmed
Web of science
Création de la notice
29/01/2008 18:35
Dernière modification de la notice
20/08/2019 14:40
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