Perioperative nerve blockade: clues from the bench.

Détails

Ressource 1Télécharger: BIB_7F045E04855C.P001.pdf (854.67 [Ko])
Etat: Public
Version: Final published version
ID Serval
serval:BIB_7F045E04855C
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Perioperative nerve blockade: clues from the bench.
Périodique
Anesthesiology Research and Practice
Auteur(s)
Suter M.R., Siegenthaler A., Decosterd I., Ji R.R.
ISSN
1687-6970 (Electronic)
ISSN-L
1687-6962
Statut éditorial
Publié
Date de publication
2011
Peer-reviewed
Oui
Volume
2011
Pages
124898
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish
Résumé
Peripheral and neuraxial nerve blockades are widely used in the perioperative period. Their values to diminish acute postoperative pain are established but other important outcomes such as chronic postoperative pain, or newly, cancer recurrence, or infections could also be influenced. The long-term effects of perioperative nerve blockade are still controversial. We will review current knowledge of the effects of blocking peripheral electrical activity in different animal models of pain. We will first go over the mechanisms of pain development and evaluate which types of fibers are activated after an injury. In the light of experimental results, we will propose some hypotheses explaining the mitigated results obtained in clinical studies on chronic postoperative pain. Finally, we will discuss three major disadvantages of the current blockade: the absence of blockade of myelinated fibers, the inappropriate duration of blockade, and the existence of activity-independent mechanisms.
Pubmed
Open Access
Oui
Création de la notice
22/08/2011 9:57
Dernière modification de la notice
20/08/2019 14:39
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