HENA, heterogeneous network-based data set for Alzheimer's disease.

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Etat: Public
Version: de l'auteur⸱e
Licence: CC BY 4.0
ID Serval
serval:BIB_7ED2F96C2385
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
HENA, heterogeneous network-based data set for Alzheimer's disease.
Périodique
Scientific data
Auteur⸱e⸱s
Sügis E., Dauvillier J., Leontjeva A., Adler P., Hindie V., Moncion T., Collura V., Daudin R., Loe-Mie Y., Herault Y., Lambert J.C., Hermjakob H., Pupko T., Rain J.C., Xenarios I., Vilo J., Simonneau M., Peterson H.
ISSN
2052-4463 (Electronic)
ISSN-L
2052-4463
Statut éditorial
Publié
Date de publication
14/08/2019
Peer-reviewed
Oui
Volume
6
Numéro
1
Pages
151
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: epublish
Résumé
Alzheimer's disease and other types of dementia are the top cause for disabilities in later life and various types of experiments have been performed to understand the underlying mechanisms of the disease with the aim of coming up with potential drug targets. These experiments have been carried out by scientists working in different domains such as proteomics, molecular biology, clinical diagnostics and genomics. The results of such experiments are stored in the databases designed for collecting data of similar types. However, in order to get a systematic view of the disease from these independent but complementary data sets, it is necessary to combine them. In this study we describe a heterogeneous network-based data set for Alzheimer's disease (HENA). Additionally, we demonstrate the application of state-of-the-art graph convolutional networks, i.e. deep learning methods for the analysis of such large heterogeneous biological data sets. We expect HENA to allow scientists to explore and analyze their own results in the broader context of Alzheimer's disease research.
Pubmed
Web of science
Open Access
Oui
Création de la notice
11/09/2019 16:30
Dernière modification de la notice
15/01/2021 8:10
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