Understanding and Enhancing Sepsis Survivorship. Priorities for Research and Practice.

Détails

ID Serval
serval:BIB_7E5D3936FBD5
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Understanding and Enhancing Sepsis Survivorship. Priorities for Research and Practice.
Périodique
American journal of respiratory and critical care medicine
Auteur⸱e⸱s
Prescott H.C., Iwashyna T.J., Blackwood B., Calandra T., Chlan L.L., Choong K., Connolly B., Dark P., Ferrucci L., Finfer S., Girard T.D., Hodgson C., Hopkins R.O., Hough C.L., Jackson J.C., Machado F.R., Marshall J.C., Misak C., Needham D.M., Panigrahi P., Reinhart K., Yende S., Zafonte R., Rowan K.M., Angus D.C.
ISSN
1535-4970 (Electronic)
ISSN-L
1073-449X
Statut éditorial
Publié
Date de publication
15/10/2019
Peer-reviewed
Oui
Volume
200
Numéro
8
Pages
972-981
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, N.I.H., Intramural ; Research Support, Non-U.S. Gov't ; Systematic Review
Publication Status: ppublish
Résumé
An estimated 14.1 million patients survive sepsis each year. Many survivors experience poor long-term outcomes, including new or worsened neuropsychological impairment; physical disability; and vulnerability to further health deterioration, including recurrent infection, cardiovascular events, and acute renal failure. However, clinical trials and guidelines have focused on shorter-term survival, so there are few data on promoting longer-term recovery. To address this unmet need, the International Sepsis Forum convened a colloquium in February 2018 titled "Understanding and Enhancing Sepsis Survivorship." The goals were to identify gaps and limitations of current research and shorter- and longer-term priorities for understanding and enhancing sepsis survivorship. Twenty-six experts from eight countries participated. The top short-term priorities identified by nominal group technique culminating in formal voting were to better leverage existing databases for research, develop and disseminate educational resources on postsepsis morbidity, and partner with sepsis survivors to define and achieve research priorities. The top longer-term priorities were to study mechanisms of long-term morbidity through large cohort studies with deep phenotyping, build a harmonized global sepsis registry to facilitate enrollment in cohorts and trials, and complete detailed longitudinal follow-up to characterize the diversity of recovery experiences. This perspective reviews colloquium discussions, the identified priorities, and current initiatives to address them.
Mots-clé
Adult, Aged, Aged, 80 and over, Biomedical Research/organization & administration, Cohort Studies, Critical Care/standards, Disabled Persons, Female, Humans, Male, Middle Aged, Practice Guidelines as Topic, Research Design, Sepsis/diagnosis, Sepsis/mortality, Sepsis/therapy, Survivorship, critical illness, rehabilitation, survivorship
Pubmed
Web of science
Création de la notice
17/06/2019 16:26
Dernière modification de la notice
05/04/2020 5:20
Données d'usage