Isolierte massive Nebennieren-blutung--eine heimtuckische Komplikation der Antikoagulation. [Isolated massive adrenal hemorrhage--an insidious complication in anticoagulation]

Détails

ID Serval
serval:BIB_7E0A5E149565
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Isolierte massive Nebennieren-blutung--eine heimtuckische Komplikation der Antikoagulation. [Isolated massive adrenal hemorrhage--an insidious complication in anticoagulation]
Périodique
Schweizerische Rundschau fur Medizin Praxis
Auteur⸱e⸱s
Marty  B., Maurer  R.
ISSN
1013-2058 (Print)
Statut éditorial
Publié
Date de publication
04/1992
Volume
81
Numéro
16
Pages
524-8
Notes
English Abstract
Journal Article
Review --- Old month value: Apr 14
Résumé
Massive bilateral adrenal hemorrhages are a rare complication of anticoagulant therapy. Among over 34,000 autopsies of adults we found six patients with such hemorrhages. Two were women and four men with a mean age of 81 years. They had been hospitalized and anticoagulated for various reasons. The hemorrhage occurred within ten days of anticoagulation, was always bilateral and massive and destroyed the adrenal cortex, thus leading to acute adreno-cortical insufficiency. The diagnosis in all patients was made only at autopsy. Main symptoms are abdominal pain, progressive hypotension, electrolyte disorders and disturbances of consciousness. In patient on anticoagulant therapy, these symptoms justify the suspicion of adrenal hemorrhage and the institution of lifesaving substitution therapy. Pathogenetically these hemorrhages are attributed to the combined effects of stress-induced adrenocortical tissue damage and increased bleeding tendency. The findings in our patients are compared with those of 83 patients from the literature.
Mots-clé
Adrenal Cortex Diseases/*chemically induced/pathology Aged Aged, 80 and over Anticoagulants/*adverse effects Female Hemorrhage/*chemically induced/pathology Humans Male
Pubmed
Création de la notice
28/01/2008 9:31
Dernière modification de la notice
20/08/2019 14:39
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