Granulomatous uveitis and congenital cataract: a rare association.

Détails

ID Serval
serval:BIB_7D2DE7CC91E4
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Granulomatous uveitis and congenital cataract: a rare association.
Périodique
Klinische Monatsblätter Für Augenheilkunde
Auteur(s)
Basso A., Mansouri K., Frueh B.E., Guex-Crosier Y.
ISSN
1439-3999[electronic], 0023-2165[linking]
Statut éditorial
Publié
Date de publication
2010
Peer-reviewed
Oui
Volume
227
Numéro
4
Pages
306-308
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
INTRODUCTION: The association of a granulomatous uveitis and congenital cataract and is rarely observed in newborn children. We describe the history of two patients presenting simultaneously with these two features in the absence of a TORCH infection. PATIENTS AND METHODS: The first patient, a boy born in 1997, presented to our hospital two days after birth with multiples Koeppe's and Busacca's nodules and bilateral cataract. The second patient, a boy born in 2006, was referred two weeks after birth. He presented with a severe unilateral granulomatous uveitis, multiples iris nodules, a high intraocular pressure of 45 mmHg and a congenital cataract. THERAPY AND OUTCOME: Lens extraction produced a rapid resolution of uveitis in these two patients. TORCH infection was ruled out in both children by history, extensive serologies performed simultaneously in mother and child or PCR of ocular fluids. CONCLUSIONS: A congenital cataract associated with a granulomatous uveitis is an extremely rare association. The removal of the lens resulted in complete resolution of the inflammation: a phacogenic mechanism could be at the origin of ocular inflammation in both cases.
Pubmed
Web of science
Création de la notice
18/05/2010 13:08
Dernière modification de la notice
20/08/2019 14:38
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