Semen quality of young men in Switzerland: a nationwide cross-sectional population-based study.
Détails
Etat: Public
Version: Final published version
Licence: CC BY-NC-ND 4.0
ID Serval
serval:BIB_7CDFC703BC9B
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Semen quality of young men in Switzerland: a nationwide cross-sectional population-based study.
Périodique
Andrology
Collaborateur⸱rice⸱s
NICER Working Group
Contributeur⸱rice⸱s
Bouchardy C., Herrmann C., Mousavi M., Bulliard J.L., Maspoli M., Bordoni A., Konzelmann I., Blanc-Moya R., Rohrmann S.
ISSN
2047-2927 (Electronic)
ISSN-L
2047-2919
Statut éditorial
Publié
Date de publication
11/2019
Peer-reviewed
Oui
Volume
7
Numéro
6
Pages
818-826
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Résumé
Sperm counts have been steadily decreasing over the past five decades with regional differences in the Western world. The reasons behind these trends are complex, but numerous insights indicate that environmental and lifestyle factors are important players.
To evaluate semen quality and male reproductive health in Switzerland.
A nationwide cross-sectional study was conducted on 2523 young men coming from all regions of Switzerland, recruited during military conscription. Semen volume, sperm concentration, motility, and morphology were analyzed. Anatomy of the genital area and testicular volume was recorded. Testicular cancer incidence rates in the general population were retrieved from Swiss regional registries.
Median sperm concentration adjusted for period of sexual abstinence was 48 million/mL. Comparing with the 5th percentile of the WHO reference values for fertile men, 17% of men had sperm concentration below 15 million/mL, 25% had less than 40% motile spermatozoa, and 43% had less than 4% normal forms. Disparities in semen quality among geographic regions, urbanization rates, and linguistic areas were limited. A larger proportion of men with poor semen quality had been exposed in utero to maternal smoking. Furthermore, testicular cancer incidence rates in the Swiss general population increased significantly between 1980 and 2014.
For the first time, a systematic sampling among young men has confirmed that semen quality is affected on a national level. The median sperm concentration measured is among the lowest observed in Europe. No specific geographical differences could be identified. Further studies are needed to determine to what extent the fertility of Swiss men is compromised and to evaluate the impact of environmental and lifestyle factors.
A significant proportion of Swiss young men display suboptimal semen quality with only 38% having sperm concentration, motility, and morphology values that met WHO semen reference criteria.
To evaluate semen quality and male reproductive health in Switzerland.
A nationwide cross-sectional study was conducted on 2523 young men coming from all regions of Switzerland, recruited during military conscription. Semen volume, sperm concentration, motility, and morphology were analyzed. Anatomy of the genital area and testicular volume was recorded. Testicular cancer incidence rates in the general population were retrieved from Swiss regional registries.
Median sperm concentration adjusted for period of sexual abstinence was 48 million/mL. Comparing with the 5th percentile of the WHO reference values for fertile men, 17% of men had sperm concentration below 15 million/mL, 25% had less than 40% motile spermatozoa, and 43% had less than 4% normal forms. Disparities in semen quality among geographic regions, urbanization rates, and linguistic areas were limited. A larger proportion of men with poor semen quality had been exposed in utero to maternal smoking. Furthermore, testicular cancer incidence rates in the Swiss general population increased significantly between 1980 and 2014.
For the first time, a systematic sampling among young men has confirmed that semen quality is affected on a national level. The median sperm concentration measured is among the lowest observed in Europe. No specific geographical differences could be identified. Further studies are needed to determine to what extent the fertility of Swiss men is compromised and to evaluate the impact of environmental and lifestyle factors.
A significant proportion of Swiss young men display suboptimal semen quality with only 38% having sperm concentration, motility, and morphology values that met WHO semen reference criteria.
Mots-clé
Adolescent, Cross-Sectional Studies, Female, Humans, Life Style, Male, Maternal Exposure/adverse effects, Oligospermia/epidemiology, Semen Analysis, Sperm Count, Sperm Motility/physiology, Spermatozoa/physiology, Switzerland/epidemiology, Young Adult, geographic variations, lifestyle factors, semen quality, sperm count, testicular cancer, young men
Pubmed
Web of science
Open Access
Oui
Création de la notice
15/06/2023 11:14
Dernière modification de la notice
25/01/2024 8:39