Homeostasis and narcolepsy.

Détails

ID Serval
serval:BIB_7CAF74C81166
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Homeostasis and narcolepsy.
Périodique
Sleep
Auteur(s)
Besset A., Tafti M., Nobile L., Billiard M.
ISSN
0161-8105[print], 0161-8105[linking]
Statut éditorial
Publié
Date de publication
12/1994
Volume
17
Numéro
8 Suppl
Pages
S29-S34
Langue
anglais
Notes
Publication types: Comparative Study ; Journal Article
Publication Status: ppublish
Résumé
Narcolepsy is characterized by irresistible daytime sleep episodes and cataplectic attacks. Because of the finding of an ultradian rhythmicity of slow-wave sleep in narcolepsy, an alteration of nonrapid eye movement sleep homeostatic regulation has been hypothesized to explain the impairment of the sleep-wakefulness cycle. This hypothesis was tested by two different methods: 1) a sleep-deprivation method (16 or 24 hours) increasing the prior sleep wakefulness and 2) a bed-rest method shortening the prior sleep wakefulness. In both studies normal subjects, sex- and age-matched to narcoleptic subjects, served as controls. Although some differences could be evidenced between the two groups, it was clearly shown that the homeostatic process was functional in narcolepsy and that narcoleptics seemed to be more sensitive to homeostatic regulation of sleep than normal subjects.
Mots-clé
Adolescent, Adult, Female, Homeostasis, Humans, Male, Narcolepsy/diagnosis, Narcolepsy/etiology, Sleep Deprivation, Sleep Stages, Sleep, REM, Time Factors, Wakefulness
Pubmed
Web of science
Création de la notice
24/01/2008 15:55
Dernière modification de la notice
20/08/2019 14:38
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