COVID-19 pédiatrique - Pathophysiologie, réponses immunitaires, prédispositions génétiques et syndrome hyperinflammatoire [Pediatric COVID-19 - Pathophysiology, immune responses, genetic predispositions, hyperinflammatory syndrome]

Détails

Ressource 1Télécharger: RMS_726_334.pdf (121.56 [Ko])
Etat: Public
Version: Final published version
Licence: CC BY-NC-ND 4.0
ID Serval
serval:BIB_7C258D1A476B
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
COVID-19 pédiatrique - Pathophysiologie, réponses immunitaires, prédispositions génétiques et syndrome hyperinflammatoire [Pediatric COVID-19 - Pathophysiology, immune responses, genetic predispositions, hyperinflammatory syndrome]
Périodique
Revue medicale suisse
Auteur⸱e⸱s
Blanchard-Rohner G., Pachlopnik Schmid J., Candotti F., Hofer M.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Statut éditorial
Publié
Date de publication
17/02/2021
Peer-reviewed
Oui
Volume
17
Numéro
726
Pages
334-337
Langue
français
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Children appeared to be initially spared by the SARS-CoV-2 pandemic, however, in spring 2020, a new clinical entity was described related to the SARS-CoV-2 infection and named multisystem inflammatory syndrome in children (MIS-C) or pediatric inflammatory multisystem syndrome (PIMS). The gravity of this inflammatory syndrome, the time interval between infection and MIS-C, the response to the various immunomodulatory treatments are all suggestive of an immunologic reaction rather than a virus-mediatred phenomenon. The pathophysiological mechanisms and possible risk factors for MIS-C have not been elucidated. In this article, we summarize what is known to date about the immune response to SARS-CoV-2 in children and about the immune response to SARS-CoV-2 in children and about the MIS-C.
Mots-clé
COVID-19, Child, Genetic Predisposition to Disease, Humans, Immunity, SARS-CoV-2, Systemic Inflammatory Response Syndrome
Pubmed
Création de la notice
01/03/2021 13:40
Dernière modification de la notice
19/08/2022 6:11
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