Deep brain stimulation Abstract. Deep brain stimulation, a neurosurgical therapy, consists of implanting electrodes in certain brain regions via which electrical impulses are applied by means of a neurostimulator (brain pacemaker). The therapeutic efficacy has been scientifically proven in various neurological and psychiatric indications. Deep Brain Stimulation offers a treatment option for severe disease progression and inadequate response to medication. Fluctuations and dyskinesias in Parkinson's disease, dystonia, refractory tremor and epilepsy, and certain pain syndromes are approved indications for deep brain stimulation in Switzerland.