Lifecourse social conditions and racial disparities in incidence of first stroke.

Détails

ID Serval
serval:BIB_7A72D1A829FE
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Lifecourse social conditions and racial disparities in incidence of first stroke.
Périodique
Annals of epidemiology
Auteur⸱e⸱s
Glymour M.M., Avendaño M., Haas S., Berkman L.F.
ISSN
1873-2585 (Electronic)
ISSN-L
1047-2797
Statut éditorial
Publié
Date de publication
12/2008
Peer-reviewed
Oui
Volume
18
Numéro
12
Pages
904-912
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
Some previous studies found excess stroke rates among black subjects persisted after adjustment for socioeconomic status (SES), fueling speculation regarding racially patterned genetic predispositions to stroke. Previous research was hampered by incomplete SES assessments, without measures of childhood conditions or adult wealth. We assess the role of lifecourse SES in explaining stroke risk and stroke disparities.
Health and Retirement Study participants age 50+ (n = 20,661) were followed on average 9.9 years for self- or proxy-reported first stroke (2175 events). Childhood social conditions (southern state of birth, parental SES, self-reported fair/poor childhood health, and attained height), adult SES (education, income, wealth, and occupational status) and traditional cardiovascular risk factors were used to predict first stroke onset using Cox proportional hazards models.
Black subjects had a 48% greater risk of first stroke incidence than whites (95% confidence interval, 1.33-1.65). Childhood conditions predicted stroke risk in both blacks and whites, independently of adult SES. Adjustment for both childhood social conditions and adult SES measures attenuated racial differences to marginal significance (hazard ratio, 1.13; 95% CI, 1.00-1.28).
Childhood social conditions predict stroke risk in black and White American adults. Additional adjustment for adult SES, in particular wealth, nearly eliminated the disparity in stroke risk between black and white subjects.
Mots-clé
African Americans/statistics & numerical data, Aged, Aged, 80 and over, Cardiovascular Diseases/epidemiology, Cardiovascular Diseases/ethnology, Ethnic Groups, European Continental Ancestry Group/statistics & numerical data, Female, Health Status Disparities, Humans, Incidence, Interviews as Topic, Life Style, Longitudinal Studies, Male, Middle Aged, Models, Statistical, Risk Factors, Social Environment, Socioeconomic Factors, Stroke/epidemiology, United States/epidemiology
Pubmed
Web of science
Création de la notice
18/10/2021 13:59
Dernière modification de la notice
04/11/2021 6:40
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