The outcomes of a second and third Gamma Knife radiosurgery for recurrent essential glossopharyngeal neuralgia.

Détails

ID Serval
serval:BIB_7A1D65626A92
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
The outcomes of a second and third Gamma Knife radiosurgery for recurrent essential glossopharyngeal neuralgia.
Périodique
Acta neurochirurgica
Auteur(s)
Balossier A., Tuleasca C. (co-premier), Muracciole X., Donnet A., Levivier M., Régis J.
ISSN
0942-0940 (Electronic)
ISSN-L
0001-6268
Statut éditorial
Publié
Date de publication
02/2020
Peer-reviewed
Oui
Volume
162
Numéro
2
Pages
271-277
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Gamma Knife radiosurgery (GKR) is a minimally invasive surgical option for drug-resistant essential glossopharyngeal neuralgia (GPN). The authors reviewed pain outcomes and complications in GPN patients who underwent a second or a third GKR for recurrent or persistent pain.
A retrospective review of all patients treated in a single center (Marseille, France) since 2004 was performed. Median prescribed dose was 85 Gy (range 70-90 Gy) at second GKR and 85 Gy at third GKR. Clinical outcome was evaluated using the Barrow Neurological Institute (BNI) scale.
Six patients (4 males, 2 females) underwent second or third GKR. The median age was 70.2 years (range 64-83 years) at second GKR and 79.8 years at third GKR. No patient had any previous surgery but GKR. Five cases had a neurovascular conflict. Median follow-up period was 12 months (range 10-94 months) after second GKR and 16 months after third GKR. The median delay to initial pain freedom response was 30 days (range 3-120 days). One patient experienced pharyngeal hypoesthesia after second GKR. After a third GKR, up to 16 months, no side effects were encountered. At the last follow-up, 3 patients were BNI I, 2 were BNI IIIa, and one did not have any improvement.
Second GKR resulted in pain reduction with low risk of additional morbidity. In patients unsuitable for microvascular decompression, GKR as a repeat or third treatment for intractable GPN is safe and effective. Third GKR was not associated with any side effects up to 16 months after the procedure.
Mots-clé
Gamma Knife, Glossopharyngeal neuralgia, Radiosurgery, Stereotactic
Pubmed
Financement(s)
Université de Lausanne / Jeune Chercheur en Recherche Clinique, Constantin Tuleasca
Création de la notice
20/12/2019 10:16
Dernière modification de la notice
03/03/2021 6:25
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