Factors influencing plasma transfusion practices in paediatric intensive care units around the world.

Détails

ID Serval
serval:BIB_79D271B3C821
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Factors influencing plasma transfusion practices in paediatric intensive care units around the world.
Périodique
Vox sanguinis
Auteur⸱e⸱s
Karam O., Demaret P., Duhamel A., Shefler A., Spinella P.C., Tucci M., Leteurtre S., Stanworth S.J.
Collaborateur⸱rice⸱s
PlasmaTV investigators
Contributeur⸱rice⸱s
Butt W., Elope C., Bain K., Erickson S., Smalley N., Dorofaeff T., Long D., Smalley N., Wiseman G., de Cléty S.C., Berghe C., de Jaeger A., Trippaerts M., Willems A., Rooze S., De Dooy J., Gilfoyle E., Wohlgemuth L., Dumitrascu M., Withington D., Hickey J., Choong K., Sanders L., Morrison G., Tijssen J., Wensley D., Krahn G., Dugas M.A., Gosselin L., Santschi M., Von Dessauer B., Ordenes N., Afshari A., Andersen L.H., Nilsson J.C., Johansen M., Jensen A.B., Mino S.C., Grunauer M., Joram N., Roullet-Renoleau N., Javouhey E., Cour-Andlauer F., Portefaix A., Brissaud O., Guichoux J., Payen V., Léger P.L., Afanetti M., Mortamet G., Maria M., Breining A., Tissieres P., Dorkenoo A., Deho A., Steinherr H., Nikolaou F., Camporesi A., Mario F., Kawasaki T., Miura S., Beca J., Rea M., Sherring C., Bushell T., Bentsen G., Dinis A., Pereira G., Vieira M., Moniz M., Alshehri S., Alasnag M., Rajab A., Pisarcikova M., Jordan I., Balcells J., Perez-Ferrer A., de Vicente Sánchez J., Moyano M.V., Martinez A.M., Lopez-Herce J., Solana M.J., González J.C., Alonso M.T., Faza M.N., Perez M.H., Amiet V., Doell C., Bordessoule A., Otter S.C., Kapitein B., Kneyber M., Brierley J., Rea V., McKeever S., Kelleher A., Scholefield B., Top A., Kelly N., Virdee S., Davis P., George S., Hawkins K.C., McCall K., Brown V., Sykes K., Levin R., MacLeod I., Horan M., Jirasek P., Inwald D., Abdulla A., Raghunanan S., Sparkes H., Hanson S., Woods K., Triscari D., Murkowski K., Ozment C., Steiner M., Nerheim D., Galster A., Higgerson R., Christie L., Martin D., Rourke L., Muszynski J., Steele L., Ajizian S., McCrory M.C., O'Brien K., Babbitt C., Felkel E., Levine G., Truemper E.J., Zink M., Nellis M., Thomas N.J., Spear D., Markovitz B., Terry J., Morzov R., Montgomery V., Michael A., Thomas M., Singleton M., Jarvis D., Nett S., Willson D., Hoot M., Bembea M., Yiu A., McKinley D., Scarlett E., Sankey J., Parikh M., Faustino E.V., Michelson K., Rilinger J., Campbell L., Gertz S., Cholette J.M., Jeyapalan A., Parker M., Bateman S., Johnson A.
ISSN
1423-0410 (Electronic)
ISSN-L
0042-9007
Statut éditorial
Publié
Date de publication
02/2017
Peer-reviewed
Oui
Volume
112
Numéro
2
Pages
140-149
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Plasma transfusions are a frequent treatment worldwide, but many studies have reported a wide variation in the indications to transfuse. Recently, an international paediatric study also showed wide variation in frequency in the use of plasma transfusions: 25% of the centres transfused plasma to >5% of their patients, whereas another 25% transfused plasma to <1% of their patients. The objective of this study was to explore the factors associated with different plasma transfusion practices in these centres.
Online survey sent to the local investigators of the 101 participating centres, in February 2016. Four areas were explored: beliefs regarding plasma transfusion, patients' case-mix in each unit, unit's characteristics, and local blood product transfusion policies and processes.
The response rate was 82% (83/101). 43% of the respondents believed that plasma transfusions can arrest bleeding, whereas 27% believe that plasma transfusion can prevent bleeding. Centres with the highest plasma transfusion rate were more likely to think that hypovolaemia and mildly abnormal coagulation tests are appropriate indications for plasma transfusions (P = 0·02 and P = 0·04, respectively). Case-mix, centre characteristics or local transfusion services were not identified as significant relevant factors.
Factors influencing plasma transfusion practices reflect beliefs about indications and the efficacy of transfusion in the prevention and management of bleeding as well as effects on coagulation tests. Educational and other initiatives to target these beliefs should be the focus of research.

Mots-clé
Adult, Blood Component Transfusion/statistics & numerical data, Female, Hemorrhage/therapy, Humans, Intensive Care Units, Pediatric, International Normalized Ratio, Male, Partial Thromboplastin Time, Physicians/psychology, Surveys and Questionnaires, blood component transfusion, child, critical illness, plasma
Pubmed
Web of science
Création de la notice
01/05/2018 13:18
Dernière modification de la notice
20/08/2019 14:36
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