Offspring of mothers with hyperglycaemia in pregnancy: The short term and long-term impact. What is new?

Détails

ID Serval
serval:BIB_796145AB9014
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Offspring of mothers with hyperglycaemia in pregnancy: The short term and long-term impact. What is new?
Périodique
Diabetes research and clinical practice
Auteur⸱e⸱s
Armengaud J.B., Ma RCW, Siddeek B., Visser GHA, Simeoni U.
ISSN
1872-8227 (Electronic)
ISSN-L
0168-8227
Statut éditorial
Publié
Date de publication
11/2018
Peer-reviewed
Oui
Volume
145
Pages
155-166
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
The continuing rise in the global prevalence of diabetes and overweight or obesity has become a major burden for global health, as the pandemic is affecting both high and low-middle income countries (LMIC). At the same time, a similar pattern has been observed for all forms of hyperglycemia in pregnancy (HIP), diabetes during pregnancy and gestational diabetes. The offspring of mothers with HIP and/or overweight-obesity is receiving increasing attention as advances in early detection and treatment of HIP did not completely prevent macrosomia and its associated short-term perinatal disorders, whilst long term consequences are observed in the mother and in offspring as it reaches adulthood. This review discusses the current developments in the consequences of HIP in the offspring, with a particular focus on its long-term health at adulthood, and on intergenerational and transgenerational effects. HIP is emerging as one of the factors that can contribute, during the window of sensitivity to environmental cues constituted by the preconception, pregnancy, and early childhood, and as an amplifying factor linked to reproduction, to the current global epidemic of diabetes and non-communicable diseases (NCDs).
Mots-clé
Diabetes, Gestational/physiopathology, Female, Humans, Hyperglycemia/complications, Infant, Newborn, Infant, Newborn, Diseases/etiology, Infant, Newborn, Diseases/pathology, Mothers, Pregnancy, Pregnancy Complications/etiology, Pregnancy Complications/pathology, Pregnancy Outcome
Pubmed
Web of science
Création de la notice
13/08/2018 12:42
Dernière modification de la notice
24/04/2021 5:33
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