Analysis of heart rate varibility at tthe onset of spontaneous ventricullar tacharrhythmias as retrieved from a defibrillator
Détails
ID Serval
serval:BIB_72903F0E8E1A
Type
Actes de conférence (partie): contribution originale à la littérature scientifique, publiée à l'occasion de conférences scientifiques, dans un ouvrage de compte-rendu (proceedings), ou dans l'édition spéciale d'un journal reconnu (conference proceedings).
Sous-type
Abstract (résumé de présentation): article court qui reprend les éléments essentiels présentés à l'occasion d'une conférence scientifique dans un poster ou lors d'une intervention orale.
Collection
Publications
Institution
Titre
Analysis of heart rate varibility at tthe onset of spontaneous ventricullar tacharrhythmias as retrieved from a defibrillator
Titre de la conférence
19th Congress of the European Society of Cardiology together with the 32nd Annual General Meeting of the Association of European Paediatric Cardiologists (AEPC)
Adresse
Stockholm, Sweden, August 24-28, 1997
ISBN
1522-9645
ISSN-L
0195-668X
Statut éditorial
Publié
Date de publication
1997
Volume
18
Série
European Heart Journal
Pages
592
Langue
anglais
Résumé
Depressed haart rate variability (HRV) is a powerful marker of future adverse
events in post-myocardial infarction patients (pts). The aim of our multicenter
study is to assess the cardiac autonomic tone using HRV analysis prior to the
onset of spontaneous and ICD-treated ventricular tachyarrhythmias (VTA) in pts
with implanted defibrillators. We performed time and frequency (FFT) analyses
on 1024 ICD-stored sinus RR intervals (average duration 12 min) preceding
VTA and compared the resuits to periods without VTA (ctrl). All episodes had
<5% premature beats.
Resuits: 61 episodes of ICD-stored VTA (maar) cycle length: 304 ± 63 ms)
from 40 pts (maan age: 55 ± 15 y, maan EF: 33 ± 16%) ware analyzed. The
following observations ware made: a significant iricrease in haart rate (VTA vs
ctrl: 711 ± 157 vs 791 ± 171 ms, p < 0.001) and reduction in total HRV (RR
interval standard deviation VTA vs ctrl: 43 ± 31 vs 52 ± 24 ms, p < 0.04),
decreased very low-frequency (InVLFpw VTA vs ctrl: 10.6 ± 1.4 vs 11.5 ± 1.3
ms2 , p < 0.001) and low-frequency fluctuations (InLFpw VTA vs ctrl: 9.4 ± 1.6
vs 9.9 ± 1.4 ms2 , p < 0.01). These findings are consistent with a sustained
adrenergic stimulation with reduced modulation of sympathetic inputs to the
haart prior to VTA onset. Moreover, the finding of low amplitude fluctuations in
the high-frequency band suggest a chronic vagal inhibition with an additional
vagal withdrawal prior to the onset of VTA (InHFpw VTA vs ctrl: 8.4 ± 1.8 vs
9.1 ± 1.6 ms2 , p < 0.001).
Conclusion: the analysis of HRV in pts suffering Erom repetitive VTA shows
at control a depressed cardiac parasympathetic activity with additional vagal
withdrawal and sympathetic activation within the 12-min window prior to the
onset of potentially fatal VTA.
events in post-myocardial infarction patients (pts). The aim of our multicenter
study is to assess the cardiac autonomic tone using HRV analysis prior to the
onset of spontaneous and ICD-treated ventricular tachyarrhythmias (VTA) in pts
with implanted defibrillators. We performed time and frequency (FFT) analyses
on 1024 ICD-stored sinus RR intervals (average duration 12 min) preceding
VTA and compared the resuits to periods without VTA (ctrl). All episodes had
<5% premature beats.
Resuits: 61 episodes of ICD-stored VTA (maar) cycle length: 304 ± 63 ms)
from 40 pts (maan age: 55 ± 15 y, maan EF: 33 ± 16%) ware analyzed. The
following observations ware made: a significant iricrease in haart rate (VTA vs
ctrl: 711 ± 157 vs 791 ± 171 ms, p < 0.001) and reduction in total HRV (RR
interval standard deviation VTA vs ctrl: 43 ± 31 vs 52 ± 24 ms, p < 0.04),
decreased very low-frequency (InVLFpw VTA vs ctrl: 10.6 ± 1.4 vs 11.5 ± 1.3
ms2 , p < 0.001) and low-frequency fluctuations (InLFpw VTA vs ctrl: 9.4 ± 1.6
vs 9.9 ± 1.4 ms2 , p < 0.01). These findings are consistent with a sustained
adrenergic stimulation with reduced modulation of sympathetic inputs to the
haart prior to VTA onset. Moreover, the finding of low amplitude fluctuations in
the high-frequency band suggest a chronic vagal inhibition with an additional
vagal withdrawal prior to the onset of VTA (InHFpw VTA vs ctrl: 8.4 ± 1.8 vs
9.1 ± 1.6 ms2 , p < 0.001).
Conclusion: the analysis of HRV in pts suffering Erom repetitive VTA shows
at control a depressed cardiac parasympathetic activity with additional vagal
withdrawal and sympathetic activation within the 12-min window prior to the
onset of potentially fatal VTA.
Création de la notice
28/01/2008 11:04
Dernière modification de la notice
20/08/2019 15:30
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