Managing 'resistance': is adherence a target for treatment?

Détails

ID Serval
serval:BIB_728A6385CA2C
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Managing 'resistance': is adherence a target for treatment?
Périodique
Current Opinion in Nephrology and Hypertension
Auteur(s)
Burnier M.
ISSN
1473-6543 (Electronic)
ISSN-L
1062-4821
Statut éditorial
Publié
Date de publication
2014
Volume
23
Numéro
5
Pages
439-443
Langue
anglais
Notes
Publication types: Journal Article Publication Status: ppublish Document Type: Review
Résumé
PURPOSE OF REVIEW: Adherence to preventive measures and prescribed medications is the cornerstone of the successful management of hypertension. The role of adherence is particularly important when treatments are not providing the expected clinical results, for example, in patients with resistant hypertension. The goal of this article is to review the recent observations regarding drug adherence in resistant hypertension.
RECENT FINDINGS: Today, the role of drug adherence as a potential cause of resistant hypertension is largely underestimated. Most studies suggest that a low adherence to the prescribed medications can affect up to 50% of patients with resistant hypertension.A good adherence to therapy is generally associated with an improved prognosis. Nonetheless, adherence should probably not be a target for treatment per se because data on adherence should always be interpreted in the view of clinical results. In our opinion, the availability of reliable data on drug adherence would be a major help for physicians to manage patients apparently resistant to therapy.
SUMMARY: The actual development of new drugs for hypertension is slow. Thus, focusing on drug adherence to the drugs available is an important way to improve blood pressure control in the population. More emphasis should be put on measuring drug adherence in patients with resistant hypertension to avoid costly investigations and treatments.
Pubmed
Web of science
Création de la notice
19/09/2014 16:48
Dernière modification de la notice
20/08/2019 14:30
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