Definition of Synchronous Oligometastatic Non-Small Cell Lung Cancer-A Consensus Report.

Détails

ID Serval
serval:BIB_7217B3C47C1C
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Definition of Synchronous Oligometastatic Non-Small Cell Lung Cancer-A Consensus Report.
Périodique
Journal of thoracic oncology
Auteur(s)
Dingemans A.C., Hendriks LEL, Berghmans T., Levy A., Hasan B., Faivre-Finn C., Giaj-Levra M., Giaj-Levra N., Girard N., Greillier L., Lantuéjoul S., Edwards J., O'Brien M., Reck M., Smit E.F., Van Schil P., Postmus P.E., Ramella S., Lievens Y., Gaga M., Peled N., Scagliotti G.V., Senan S., Paz-Ares L., Guckenberger M., McDonald F., Ekman S., Cufer T., Gietema H., Infante M., Dziadziuszko R., Peters S., Porta R.R., Vansteenkiste J., Dooms C., de Ruysscher D., Besse B., Novello S.
ISSN
1556-1380 (Electronic)
ISSN-L
1556-0864
Statut éditorial
Publié
Date de publication
12/2019
Peer-reviewed
Oui
Volume
14
Numéro
12
Pages
2109-2119
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Improved outcome has been shown in patients with synchronous oligometastatic (sOM) NSCLC when treated with radical intent. As a uniform definition of sOM NSCLC is lacking, we developed a definition and diagnostic criteria by a consensus process.
A pan-European multidisciplinary consensus group was established. Consensus questions were built on the basis of current controversies, and definitions were extracted from a survey, cases and a systematic review. This statement was formulated during a consensus meeting.
It was determined that definition of sOM NSCLC is relevant when a radical treatment that may modify the disease course (leading to long-term disease control) is technically feasible for all tumor sites with acceptable toxicity. On the basis of the review, a maximum of five metastases and three organs was proposed. Mediastinal lymph node involvement was not counted as a metastatic site. Fludeoxyglucose F 18 positron emission tomography-computed tomography and brain imaging were considered mandatory. A dedicated liver magnetic resonance imaging scan was advised for a solitary liver metastasis, and thoracoscopy and biopsies of distant ipsilateral pleural sites were recommended for a solitary pleural metastasis. For mediastinal staging, fludeoxyglucose F 18 positron emission tomography-computed tomography was deemed the minimum requirement, with pathological confirmation recommended if this influences the treatment strategy. Biopsy of a solitary metastatic location was mandated unless the multidisciplinary team is of the opinion that the risks outweigh the benefits.
A multidisciplinary consensus statement on the definition and staging of sOM NSCLC has been formulated. This statement will help to standardize inclusion criteria in future clinical trials.
Mots-clé
Non-small cell lung cancer, consensus definition, oligometastatic disease, staging, Consensus definition, Non–small cell lung cancer, Oligometastatic disease, Staging
Pubmed
Web of science
Open Access
Oui
Création de la notice
16/08/2019 20:02
Dernière modification de la notice
11/09/2020 5:22
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