A unique signature identifies a family of zinc-dependent metallopeptidases

Détails

ID Serval
serval:BIB_7039DF96B340
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
A unique signature identifies a family of zinc-dependent metallopeptidases
Périodique
FEBS Letters
Auteur(s)
Jongeneel  C. V., Bouvier  J., Bairoch  A.
ISSN
0014-5793 (Print)
Statut éditorial
Publié
Date de publication
01/1989
Volume
242
Numéro
2
Pages
211-4
Notes
Journal Article --- Old month value: Jan 2
Résumé
The primary sequence motif HExxH has been found in many zinc-dependent endopeptidases. We show that a larger signature comprising this sequence is common to most of the known zinc-dependent endopeptidases, and that the presence of the signature can be indicative of membership in the family. A search of the protein sequence databases for entries containing the signature retrieved several unexpected potential zinc endopeptidases.
Mots-clé
Amino Acid Sequence Animals Humans *Metalloendopeptidases Structure-Activity Relationship
Pubmed
Web of science
Open Access
Oui
Création de la notice
24/01/2008 15:39
Dernière modification de la notice
20/08/2019 14:28
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