Utilite de la procalcitonine dans le diagnostic et le suivi des infections chez les patients neutropeniques febriles. [Utility of procalcitonin for the diagnosis and the follow-up of infections in febrile neutropenic patients]

Détails

ID Serval
serval:BIB_6FD19B7CD714
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Utilite de la procalcitonine dans le diagnostic et le suivi des infections chez les patients neutropeniques febriles. [Utility of procalcitonin for the diagnosis and the follow-up of infections in febrile neutropenic patients]
Périodique
Revue Médicale Suisse
Auteur⸱e⸱s
Robinson  J. O., Calandra  T., Marchetti  O.
ISSN
1660-9379 (Print)
Statut éditorial
Publié
Date de publication
03/2005
Volume
1
Numéro
13
Pages
878-82, 885-6
Notes
English Abstract
Journal Article
Review --- Old month value: Mar 30
Résumé
Procalcitonin is a marker of severe bacterial infections in non-neutropenic patients. The goal of this review is to assess its utility in the management of neutropenic patients. A delayed treatment of infection in this setting results in severe morbidity and high mortality. As traditional diagnostic tools often fail to exclude infection when fever occurs, all these patients receive empirical antimicrobial therapies during long periods of time. Present knowledge suggests that procalcitonin may contribute to identify patients in whom 1) antibiotics could be stopped in the absence of bacterial infection, 2) investigations and adjustments of the antimicrobial therapy for persistent fever are needed. The use of procalcitonin for the management of febrile neutropenic patients should be studied prospectively.
Mots-clé
Anti-Bacterial Agents/therapeutic use Bacterial Infections/*complications/*diagnosis/drug therapy Biological Markers/*blood Calcitonin/*blood Diagnosis, Differential Fever/*etiology Glycoproteins Humans Neutropenia/*etiology Protein Precursors/*blood
Pubmed
Création de la notice
25/01/2008 13:33
Dernière modification de la notice
20/08/2019 14:28
Données d'usage