Vacuum assisted venous drainage does not increase trauma to blood cells.

Détails

ID Serval
serval:BIB_6EEAC0B21CC3
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Vacuum assisted venous drainage does not increase trauma to blood cells.
Périodique
ASAIO journal (American Society for Artificial Internal Organs : 1992)
Auteur⸱e⸱s
Mueller X.M., Tevaearai H.T., Horisberger J., Augstburger M., Burki M., von Segesser L.K.
ISSN
1058-2916
Statut éditorial
Publié
Date de publication
2001
Peer-reviewed
Oui
Volume
47
Numéro
6
Pages
651-4
Langue
anglais
Notes
Publication types: Comparative Study ; Journal Article - Publication Status: ppublish
Résumé
Although gravity drainage has been the standard technique for cardiopulmonary bypass (CPB), the development of min imally invasive techniques for cardiac surgery has renewed interest in using vacuum assisted venous drainage (VAVD) Dideco (Mirandola, Italy) has modified the D903 Avant oxygenator to apply a vacuum to its venous reservoir. The impact of VAVD on blood damage with this device is analyzed. Six calves (mean body weight, 71.3 +/- 4.1 kg) were con nected to CPB by jugular venous and carotid arterial cannu lation, with a flow rate of 4-4.51 L/min for 6 h. They were assigned to gravity drainage (standard D903 Avant oxygen ator, n = 3) or VAVD (modified D903 Avant oxygenator, n = 3). The animals were allowed to survive for 7 days. A standard battery of blood samples was taken before bypass, throughout bypass, and 24 h, 48 h, and 7 days after bypass. Analysis of variance was used for repeated measurements. Thrombocyte and white blood cell counts, corrected by hematocrit and normalized by prebypass values, were not significantly different between groups throughout all study periods. The same holds true for hemolytic parameters (lactate dehydrogenase [LDH] and plasma hemoglobin). Both peaked at 24 hr in the standard and VAVD groups: LDH, 2,845 +/- 974 IU/L vs. 2,537 +/- 476 IU/L (p = 0.65), respectively; and plasma hemoglobin, 115 +/- 31 mg/L vs. 89 +/- 455 mg/L (p = 0.45), respectively. In this experimental setup with prolonged perfusion time, VAVD does not increase trauma to blood cells in comparison with standard gravity drainage.
Mots-clé
Animals, Blood Cells, Cardiopulmonary Bypass, Cattle, Extracorporeal Circulation, Gravitation, Hematocrit, Hemoglobins, L-Lactate Dehydrogenase, Leukocyte Count, Platelet Count, Suction, Vacuum, Veins, Vena Cava, Superior
Pubmed
Web of science
Création de la notice
14/02/2008 15:16
Dernière modification de la notice
20/08/2019 15:28
Données d'usage