Activity and exploratory behavior after lesions of the medial entorhinal cortex in the woodmouse (Apodemus sylvaticus).

Détails

ID Serval
serval:BIB_6DF074E75D22
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Activity and exploratory behavior after lesions of the medial entorhinal cortex in the woodmouse (Apodemus sylvaticus).
Périodique
Behavioral and Neural Biology
Auteur⸱e⸱s
Schenk F., Inglin F., Gyger M.
ISSN
0163-1047 (Print)
ISSN-L
0163-1047
Statut éditorial
Publié
Date de publication
1983
Peer-reviewed
Oui
Volume
37
Numéro
1
Pages
89-107
Langue
anglais
Résumé
The effects of bilateral electrolytic lesions of the entorhinal cortex were studied in male adult woodmice. Experiments were designed to allow separate analysis of the basal activity level and exploratory behavior. Activity recording was conducted in three situations: (a) 24-hr wheel running in the home cage pre- and postoperatively; (b) 24-hr activity composition in a large enclosure over 4 days, 5 to 9 days postoperatively; and (c) sequence and duration of visits in a residential plus maze 11 to 14 days postoperatively. Medial entorhinal cortex lesion involving the para- and presubiculum increased the 24-hr amount of movements in the enclosure (b) without increasing wheel running in any situation (a or b). This lesion also enhanced the locomotor reactivity to being introduced into the plus maze and impaired exploratory behavior. This last effect was equally apparent when the whole situation was new or when part of the familiar maze was modified. Lesioned woodmice did notice the new element but did not show active focalization of their behavior on that element. Data showed that lesion induced hyperactivity and changes of exploratory behavior were not necessarily associated. Novelty detection was performed but it is not clear now on what information this discrimination was based.
Mots-clé
Animals, Discrimination Learning/physiology, Exploratory Behavior/physiology, Limbic System/physiology, Male, Motor Activity/physiology, Muridae, Social Environment
Pubmed
Web of science
Création de la notice
24/01/2008 13:28
Dernière modification de la notice
20/08/2019 14:27
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