WEIGHT TRAJECTORIES DO NOT INFLUENCE DIABETES CONTROL. A PROSPECTIVE STUDY IN SWITZERLAND (COLAUS STUDY).

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Accès restreint UNIL
Etat: Public
Version: Après imprimatur
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ID Serval
serval:BIB_6D493258B050
Type
Mémoire
Sous-type
(Mémoire de) maîtrise (master)
Collection
Publications
Institution
Titre
WEIGHT TRAJECTORIES DO NOT INFLUENCE DIABETES CONTROL. A PROSPECTIVE STUDY IN SWITZERLAND (COLAUS STUDY).
Auteur⸱e⸱s
DUCRAUX P.
Directeur⸱rice⸱s
MARQUES-VIDAL P.
Codirecteur⸱rice⸱s
WAEBER G.
Détails de l'institution
Université de Lausanne, Faculté de biologie et médecine
Statut éditorial
Acceptée
Date de publication
2021
Langue
anglais
Nombre de pages
22
Résumé
The objective was to identify anthropometric trajectories among subjects with type 2 diabetes, and associate them with glycaemic control.
A prospective study including 268 community-dwelling participants with type 2 diabetes (34% women, mean age 68.7±8.9 years) followed for 10.7 years (range: 8.8-13.6 years). Type 2 diabetes control was considered for 1) fasting plasma glucose (FPG) <7.0 mmol/L, or 2) HbA1c<7.0% (53 nmol/mol). Changes in weight or waist and weight variability were considered.
One half (FPG) and one third (HbA1c) of participants presented with uncontrolled type 2 diabetes. Half of the participants presented with obesity and 75% with abdominal obesity. During follow-up, half of the participants maintained their weight, 25% gained >5 kg, and 25% lost <5 kg; almost half increased their waist by >5 cm. Using FPG as criterion, participants who lost >5 cm waist were more likely to be controlled: multivariable-adjusted odds ratio (OR) and 95% confidence interval (CI): 3.10 (1.23-7.78). Participants with controlled diabetes also presented with a higher weight variability: multivariable adjusted mean±standard error 4.8±0.3 vs. 3.9±0.3 kg, p=0.028. Using HbA1c as criterion, participants who lost >5 kg were less likely to be controlled: OR and (95% CI): 0.35 (0.18-0.66). Similar findings were obtained when restricting the analysis to participants with type 2 diabetes throughout the whole study period. In a Swiss community-based sample of participants with type 2 diabetes, diabetes control rates are low; neither weight nor waist changes were significantly and consistently associated with type 2 diabetes control.
Mots-clé
Diabetes, Diabetes management, Weight, Epidemiology
Création de la notice
07/09/2022 15:37
Dernière modification de la notice
13/01/2023 7:47
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