Targeting metastatic prostate cancer: the search for innovative systemic therapies.

Détails

ID Serval
serval:BIB_6D02A35AE285
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Targeting metastatic prostate cancer: the search for innovative systemic therapies.
Périodique
Oncology (Williston Park, N.Y.)
Auteur⸱e⸱s
Berthold D.R., Moore M.J.
ISSN
0890-9091 (Print)
ISSN-L
0890-9091
Statut éditorial
Publié
Date de publication
12/2006
Peer-reviewed
Oui
Volume
20
Numéro
14
Pages
1787-91; discussion 1791-6
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish

Résumé
Metastatic hormone-resistant prostate cancer has proven largely resistant to cytotoxic therapy. Since 2004, docetaxel (Taxotere)/prednisone has become the standard chemotherapy used to treat advanced hormone-resistant prostate cancer. However, the survival advantage is modest and a significant number of patients do not respond to chemotherapy. It is hoped that an increased understanding of the mechanisms underlying the progression of prostate cancer will lead to new treatment modalities. With the growing number of biologic and targeted agents under development, the potential armamentarium of prostate cancer treatments is steadily growing. However, none of the new treatment modalities has yet been shown to be more effective than standard treatments. This article will provide an overview of targeted or innovative therapies in the treatment of prostate cancer.

Mots-clé
Androgen Antagonists/therapeutic use, Antineoplastic Combined Chemotherapy Protocols/therapeutic use, Bone Neoplasms/drug therapy, Bone Neoplasms/secondary, Drug Resistance, Neoplasm, Humans, Male, Prostatic Neoplasms/drug therapy, Prostatic Neoplasms/surgery
Pubmed
Création de la notice
30/11/2016 23:28
Dernière modification de la notice
20/08/2019 14:26
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