Cerebrovascular complications of bacterial meningitis in adults.

Détails

ID Serval
serval:BIB_6B961E6A1205
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Cerebrovascular complications of bacterial meningitis in adults.
Périodique
Neurology
Auteur(s)
Pfister H.W., Borasio G.D., Dirnagl U., Bauer M., Einhäupl K.M.
ISSN
0028-3878 (Print)
ISSN-L
0028-3878
Statut éditorial
Publié
Date de publication
1992
Volume
42
Numéro
8
Pages
1497-1504
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish
Résumé
We performed a prospective study of the type, frequency, temporal profile, and prognostic role of cerebrovascular complications in 86 adults with bacterial meningitis. Cerebral angiography was performed in 27 patients (31.4%) who had focal deficits either clinically, on cranial CT, or both, and in patients who had persistent coma without explained cause despite 3 days of antibiotic therapy. Alterations of the vessel systems, including involvement of major arteries at the base of the brain, medium-sized arteries, small vessels, and major sinuses and cortical veins, were present in 13 of the 27 patients who had angiography. Typical cerebrovascular complications were arterial narrowing of the supraclinoid portion of the internal carotid artery; vessel wall irregularities, focal dilatations, and occlusions of distal branches of the middle cerebral artery; focal abnormal parenchymal blush; and thrombosis of the sagittal superior sinus and cortical veins. Prognosis for those patients with cerebrovascular complications was unfavorable. Six patients died, one remained in a vegetative state, four were moderately or slightly disabled, and only two recovered completely. The study showed that angiographically documented cerebrovascular complications are the most frequent intracranial complications in bacterial meningitis of the adult (37.1%) and are major determinants in the prognosis of this disease.
Mots-clé
Adult, Aged, Aged, 80 and over, Cerebral Angiography, Cerebrospinal Fluid/microbiology, Cerebrovascular Disorders/etiology, Cerebrovascular Disorders/physiopathology, Disability Evaluation, Female, Humans, Male, Meningitis, Bacterial/cerebrospinal fluid, Meningitis, Bacterial/complications, Middle Aged, Prognosis, Prospective Studies, Time Factors
Pubmed
Web of science
Création de la notice
13/01/2014 16:44
Dernière modification de la notice
20/08/2019 14:25
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