The tripartite motif family identifies cell compartments.

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ID Serval
serval:BIB_6A96E2C992E0
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Production externe
Titre
The tripartite motif family identifies cell compartments.
Périodique
EMBO Journal
Auteur⸱e⸱s
Reymond A., Meroni G., Fantozzi A., Merla G., Cairo S., Luzi L., Riganelli D., Zanaria E., Messali S., Cainarca S., Guffanti A., Minucci S., Pelicci P.G., Ballabio A.
ISSN
0261-4189 (Print)
ISSN-L
0261-4189
Statut éditorial
Publié
Date de publication
2001
Volume
20
Numéro
9
Pages
2140-2151
Langue
anglais
Résumé
A functional genomic approach, based on systematic data gathering, was used to characterize a family of proteins containing a tripartite motif (TRIM). A total of 37 TRIM genes/proteins were studied, 21 of which were novel. The results demonstrate that TRIM proteins share a common function: by means of homo-multimerization they identify specific cell compartments.
Mots-clé
Amino Acid Motifs/physiology, Animals, Blotting, Northern, Carrier Proteins, Cell Compartmentation/physiology, Cell Line, Chromosome Mapping, Cloning, Molecular, Databases, Factual, Embryo, Mammalian, Humans, In Situ Hybridization, Mice, Molecular Sequence Data, Multigene Family/genetics, Mutagenesis, Site-Directed, Nerve Tissue Proteins, Organ Specificity, Protein Binding/physiology, Protein Structure, Tertiary/physiology, Proteins/physiology, Sequence Homology, Amino Acid, Subcellular Fractions/metabolism, Two-Hybrid System Techniques
DOI
10.1093/emboj/20.9.2140
Pubmed
11331580
Web of science
000168597600004
Open Access
Oui
Création de la notice
24/01/2008 16:52
Dernière modification de la notice
20/08/2019 15:25
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