Mapping the structural core of human cerebral cortex.

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Etat: Public
Version: de l'auteur⸱e
ID Serval
serval:BIB_6A4D544D8AB8
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Mapping the structural core of human cerebral cortex.
Périodique
PLoS Biology
Auteur⸱e⸱s
Hagmann P., Cammoun L., Gigandet X., Meuli R., Honey C.J., Wedeen V.J., Sporns O.
ISSN
1545-7885
Statut éditorial
Publié
Date de publication
2008
Peer-reviewed
Oui
Volume
6
Numéro
7
Pages
e159
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
Patric Cammoun, Leila Gigandet, Xavier Meuli, Reto Honey, Christopher J Wedeen, Van J Sporns, Olaf
Résumé
Structurally segregated and functionally specialized regions of the human cerebral cortex are interconnected by a dense network of cortico-cortical axonal pathways. By using diffusion spectrum imaging, we noninvasively mapped these pathways within and across cortical hemispheres in individual human participants. An analysis of the resulting large-scale structural brain networks reveals a structural core within posterior medial and parietal cerebral cortex, as well as several distinct temporal and frontal modules. Brain regions within the structural core share high degree, strength, and betweenness centrality, and they constitute connector hubs that link all major structural modules. The structural core contains brain regions that form the posterior components of the human default network. Looking both within and outside of core regions, we observed a substantial correspondence between structural connectivity and resting-state functional connectivity measured in the same participants. The spatial and topological centrality of the core within cortex suggests an important role in functional integration.
Mots-clé
Adult, Brain Mapping, Cerebral Cortex, Diffusion Magnetic Resonance Imaging, Humans, Imaging, Three-Dimensional, Male, Models, Neurological, Nerve Net
Pubmed
Web of science
Open Access
Oui
Création de la notice
29/01/2009 20:06
Dernière modification de la notice
20/08/2019 15:25
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