Applications cliniques du dosage radioimmunologique de l'hormone antidiuretique [Clinical application of the radioimmunological measurement of the antidiuretic hormone]

Détails

ID Serval
serval:BIB_679D6D27A80D
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Applications cliniques du dosage radioimmunologique de l'hormone antidiuretique [Clinical application of the radioimmunological measurement of the antidiuretic hormone]
Périodique
Schweizerische Medizinische Wochenschrift
Auteur⸱e⸱s
Merkelbach  U., Dubied  M. C., Gaillard  R., Vallotton  M. B.
ISSN
0036-7672 (Print)
Statut éditorial
Publié
Date de publication
12/1975
Volume
105
Numéro
50
Pages
1690-2
Notes
English Abstract
Journal Article --- Old month value: Dec 13
Résumé
A radioimmunoassay specific for arginine-vasopressin (AVP) developed in recent years has been applied to measurement of urinary AVP during physiological and clinical studies. Daily excretion of AVP was 34 +/- 10 ng (mean +/- SD) in 17 female normals and 69 +/- 45 ng in 17 male normals, this being a significant difference (p less than 0.01). After osmolar load (Carter-Robbins test) hourly excretion of AVP increased significantly in 7 males from 1.3 to 3.1 ng/h and in 6 females from 1.7 to 6.5 ng/h. Again the difference between male and female normals was significant. In both sexes a significant correlation between AVP excretion and either plasma osmolality or free-water clearance was found. When the osmolar load test was performed under constant angiotensin II perfusion in male subjects, their AVP excretion was significantly more elevated; this confirmed in man the hypothesis that angiotensin II is a stimulus to AVP secretion. Preliminary results of AVP excretion and response to osmolar load in diabetes insipidus are reported. Exceedingly high rate of excretion of AVP up to 55 330 ng/24 h have been found in cases of bronchial carcinoma with dilutional hyponatremia.
Mots-clé
Aldosterone/urine Angiotensin II Bronchial Neoplasms/physiopathology Diabetes Insipidus/physiopathology Female Humans Male Osmolar Concentration Thirst Vasopressins/*analysis Water-Electrolyte Balance
Pubmed
Web of science
Création de la notice
15/02/2008 17:58
Dernière modification de la notice
20/08/2019 15:23
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