Cycling through metabolism.

Détails

ID Serval
serval:BIB_66F53146DC4A
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Cycling through metabolism.
Périodique
EMBO Molecular Medicine
Auteur(s)
Aguilar V., Fajas L.
ISSN
1757-4684 (Electronic)
ISSN-L
1757-4676
Statut éditorial
Publié
Date de publication
2010
Volume
2
Numéro
9
Pages
338-348
Langue
anglais
Résumé
Since the discovery of cyclins, the role of cell cycle regulators in the control of cell proliferation has been extensively studied. It is clear that proliferation requires an adapted metabolic response of the cells; hence the regulation of cell cycle must be linked to metabolic control. While at a much slower pace, the impact that the activities of cell cycle regulators such as cyclins, cyclin dependent kinases or E2F factor, transcription factor have on cell metabolism are also being uncovered. Here we will focus on recent data implicating cell cycle regulators in metabolic control, with particular attention to studies performed using mouse models. Furthermore, we will discuss the possible relevance of these findings in the context of metabolic disorders such as obesity or diabetes.
Mots-clé
Adipogenesis, Animals, Cell Cycle Proteins/metabolism, Cell Cycle Proteins/physiology, Cyclin-Dependent Kinases/metabolism, Cyclins/metabolism, Cyclins/physiology, E2F Transcription Factors/metabolism, Energy Metabolism, Metabolic Diseases/metabolism, Mice
Pubmed
Web of science
Open Access
Oui
Création de la notice
07/03/2013 15:47
Dernière modification de la notice
20/08/2019 14:22
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