Gliomas in children: a review

Détails

ID Serval
serval:BIB_630AD9991D5E
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Gliomas in children: a review
Périodique
Child's Nervous System
Auteur⸱e⸱s
Rilliet  B., Vernet  O.
ISSN
0256-7040 (Print)
Statut éditorial
Publié
Date de publication
11/2000
Volume
16
Numéro
10-11
Pages
735-41
Notes
Journal Article
Review --- Old month value: Nov
Résumé
The management and prognosis of gliomas are significantly different in children and in adults. Fortunately, the proportion of gliomas that are malignant is smaller in children than in the adult population. The different types of gliomas encountered in the pediatric population are reviewed, taking account of the most recent contributions on this subject. The importance of considering both localization and histological classification for better definition of the prognostic factors of each subgroup is emphasized. A brief review of the possible causes of gliomas is presented. Unfortunately, the information obtained by molecular and genetic study of these tumors has still not resulted in anything that can help the children suffering from gliomas in a concrete way. Surgery, with all its recent refinements, remains the best treatment for the majority of benign gliomas providing they can be removed without unacceptable sequelae. The role of chemotherapy has emerged recently for the treatment of nonresectable low-grade gliomas, such as hypothalamic-chiasmatic tumors, especially for infants, in whom the adverse effects of radiotherapy can be severe and irreversible. On the eve of the new millennium, there is renewed hope that the problem of malignant gliomas will be solved in the not-too-distant future.
Mots-clé
Brain Neoplasms/diagnosis/mortality/*surgery Child Glioma/diagnosis/mortality/*surgery Humans Prognosis Survival Rate
Pubmed
Web of science
Création de la notice
25/01/2008 14:13
Dernière modification de la notice
20/08/2019 15:19
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