Positive EtG findings in hair as a result of a cosmetic treatment.

Détails

ID Serval
serval:BIB_62A6EE453580
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Positive EtG findings in hair as a result of a cosmetic treatment.
Périodique
Forensic Science International
Auteur(s)
Sporkert F., Kharbouche H., Augsburger M.P., Klemm C., Baumgartner M.R.
ISSN
1872-6283 (Electronic)
ISSN-L
0379-0738
Statut éditorial
Publié
Date de publication
2012
Peer-reviewed
Oui
Volume
218
Numéro
1-3
Pages
97-100
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article
Résumé
In a case of a driving ability assessment, hair analysis for ethyl glucuronide (EtG) was requested by the authorities. The person concerned denied alcohol consumption and did not present any clinical sign of alcoholism. However, EtG was found in concentrations of up to 910pg/mg in hair from different sampling dates suggesting an excessive drinking behavior. The person declared to use a hair lotion on a regularly base. To evaluate a possible effect of the hair lotion, prospective blood and urine controls as well as hair sampling of scalp and pubic hair were performed. The traditional clinical biomarkers of ethanol consumption, CDT and GGT, were inconspicuous in three blood samples taken. EtG was not detected in all collected urine samples. The hair lotion was transmitted to our laboratory. The ethanol concentration in this lotion was determined with 35g/L. The EtG immunoassay gave a positive result indicating EtG, which could be confirmed by GC-MS/MS-NCI. In a follow-up experiment the lotion was applied to the hair of a volunteer over a period of six weeks. After this treatment, EtG could be measured in the hair at a concentration of 72pg/mg suggesting chronic and excessive alcohol consumption. Overnight incubation of EtG free hair in the lotion yielded an EtG concentration of 140pg/mg. In the present case, the positive EtG hair findings could be interpreted as the result of an EtG containing hair care product. To our knowledge, the existence of such a product has not yet been reported, and it is exceptionally unusual to find EtG in cosmetics. Therefore, external sources for hair contamination should always be taken into account when unusual cosmetic treatment is mentioned. In those cases, it is recommended to analyze the hair product for a possible contamination with EtG. The analysis of body hair can help to reveal problems occurring from cosmetic treatment of head hair. As a consequence, the assessment of drinking behavior should be based on more than one diagnostic parameter.
Mots-clé
Adult, Ethanol/analysis, Female, Gas Chromatography-Mass Spectrometry, Glucuronates/analysis, Hair/chemistry, Hair Preparations/adverse effects, Hair Preparations/chemistry, Humans, Solvents/analysis
Pubmed
Web of science
Création de la notice
01/03/2012 16:46
Dernière modification de la notice
20/08/2019 15:19
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