Interobserver and intraobserver variability of the apparent diffusion coefficient in treated malignant hepatic lesions on a 3.0T machine: measurements in the whole lesion versus in the area with the most restricted diffusion.

Détails

ID Serval
serval:BIB_6280EC48CD8D
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Interobserver and intraobserver variability of the apparent diffusion coefficient in treated malignant hepatic lesions on a 3.0T machine: measurements in the whole lesion versus in the area with the most restricted diffusion.
Périodique
Journal of Magnetic Resonance Imaging
Auteur(s)
Lu T.L., Meuli R.A., Marques-Vidal P.M., Bize P., Denys A., Schmidt S.
ISSN
1522-2586[electronic], 1053-1807[linking]
Statut éditorial
Publié
Date de publication
2010
Volume
32
Numéro
3
Pages
647-653
Langue
anglais
Résumé
PURPOSE: To assess the inter/intraobserver variability of apparent diffusion coefficient (ADC) measurements in treated hepatic lesions and to compare ADC measurements in the whole lesion and in the area with the most restricted diffusion (MRDA).
MATERIALS AND METHODS: Twenty-five patients with treated malignant liver lesions were examined on a 3.0T machine. After agreeing on the best ADC image, two readers independently measured the ADC values in the whole lesion and in the MRDA. These measurements were repeated 1 month later. The Bland-Altman method, Spearman correlation coefficients, and the Wilcoxon signed-rank test were used to evaluate the measurements.
RESULTS: Interobserver variability for ADC measurements in the whole lesion and in the MRDA was 0.17 x 10(-3) mm(2)/s [-0.17, +0.17] and 0.43 x 10(-3) mm(2)/s [-0.45, +0.41], respectively. Intraobserver limits of agreement could be as low as [-0.10, +0.12] 10(-3) mm(2)/s and [-0.20, +0.33] 10(-3) mm(2)/s for measurements in the whole lesion and in the MRDA, respectively.
CONCLUSION: A limited variability in ADC measurements does exist, and it should be considered when interpreting ADC values of hepatic malignancies. This is especially true for the measurements of the minimal ADC.
Mots-clé
liver neoplasms, diffusion weighted imaging, apparent diffusion coefficient, interobserver variability, intraobserver variability, focal liver-lesions, hepatocellular-carcinoma, adc measurements, chemoembolization, reproducibility, breathhold, sequences, abdomen, tumors, mri
Pubmed
Web of science
Open Access
Oui
Création de la notice
29/09/2010 15:14
Dernière modification de la notice
20/08/2019 14:19
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