Characterisation of protracted low-level exposure to uranium in the workplace: A comparison of two approaches

Détails

ID Serval
serval:BIB_6230778D2F20
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Characterisation of protracted low-level exposure to uranium in the workplace: A comparison of two approaches
Périodique
International Journal of Hygiene and Environmental Health
Auteur⸱e⸱s
Guseva Canu Irina, Laurier Dominique, Caër-Lorho Sylvaine, Samson Eric, Timarche M., Auriol B., Bérard P., Collomb Philippe, Quesne B., Blanchardon E.
ISSN
1618-131X (Electronic)
ISSN-L
1438-4639
Statut éditorial
Publié
Date de publication
07/2010
Peer-reviewed
Oui
Volume
213
Numéro
4
Pages
270-277
Langue
anglais
Notes
Publication types: Comparative Study ; Journal Article
Publication Status: ppublish
Résumé
Retrospective estimates of internal doses received by workers in the nuclear industry following intake of radionuclides, based on bioassay data, are a benchmark method in epidemiological studies. Nonetheless, full information relative to thousands of people included in an epidemiological cohort is rarely available, thus implying difficulties to estimate exposure precisely. To evaluate the cumulative exposure to uranium in a cohort of the AREVA NC Pierrelatte plant workers, we compared the epidemiological Job Exposure Matrix (JEM) method with the dosimetric method based on biological monitoring of exposure for 30 workers randomly selected within the cohort. A moderate to strong correlation was observed between the estimators resulting from the two approaches, thereby validating the JEM as a tool that can be used to characterise cumulative exposure to uranium in the cohort. In addition, this study showed that the JEM is a valuable complement to the interpretation of bioassy, (1) in providing information on exposure periods as well as on physical and chemical form of the radionuclides and (2) in compensating for the lack of exposure data regarding the very earliest periods. Combining the two methods may improve the precision in reconstructing cumulative exposure for epidemiological studies.

Mots-clé
Adult, Cohort Studies, Feces/chemistry, Humans, Lung/chemistry, Occupational Exposure/analysis, Radiation Monitoring/methods, Radioactive Pollutants/analysis, Radioactive Pollutants/urine, Radiometry, Uranium/analysis, Uranium/urine
Pubmed
Web of science
Création de la notice
12/09/2017 15:06
Dernière modification de la notice
20/08/2019 14:19
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