Diagnostic performance of Fluorine-18-Fluorodeoxyglucose positron emission tomography in patients with chronic inflammatory bowel disease: a systematic review and a meta-analysis.

Détails

ID Serval
serval:BIB_61F28E50135A
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Diagnostic performance of Fluorine-18-Fluorodeoxyglucose positron emission tomography in patients with chronic inflammatory bowel disease: a systematic review and a meta-analysis.
Périodique
Journal of Crohn's & colitis
Auteur(s)
Treglia G., Quartuccio N., Sadeghi R., Farchione A., Caldarella C., Bertagna F., Fania P., Cistaro A.
ISSN
1876-4479 (Electronic)
ISSN-L
1873-9946
Statut éditorial
Publié
Date de publication
06/2013
Peer-reviewed
Oui
Volume
7
Numéro
5
Pages
345-354
Langue
anglais
Notes
Publication types: Journal Article ; Meta-Analysis ; Review
Publication Status: ppublish
Résumé
To systematically review and meta-analyze published data about the diagnostic performance of Fluorine-18-Fluorodeoxyglucose ((18)F-FDG) positron emission tomography (PET) and PET/computed tomography (PET/CT) in patients with chronic inflammatory bowel disease (IBD).
A comprehensive computer literature search of studies published through May 2012 regarding (18)F-FDG-PET and PET/CT in patients with IBD was performed. All retrieved studies were reviewed and qualitatively analyzed. Pooled sensitivity, specificity, positive and negative likelihood ratio (LR+ and LR-) and diagnostic odd ratio (DOR) of (18)F-FDG PET and PET/CT in patients with IBD on a per segment-based analysis were calculated. The area under the ROC curve was calculated to measure the accuracy of (18)F-FDG PET and PET/CT in patients with IBD.
Nineteen studies comprising 454 patients with suspected IBD were included in the qualitative analysis (systematic review) and discussed. The quantitative analysis (meta-analysis) of seven selected studies (including 219 patients with IBD) provided the following results on a per segment-based analysis: sensitivity was 85% [95% confidence interval (95%CI) 81-88%], specificity 87% (95%CI 84-90%), LR+ 6.19 (95%CI: 2.86-13.41), LR- 0.19 (95%CI: 0.10-0.34), and DOR 44.35 (95%CI: 11.77-167.07). The area under the ROC curve was 0.933.
In patients with suspected IBD (18)F-FDG PET and PET/CT demonstrated good sensitivity and specificity, being accurate methods in this setting. Nevertheless, the literature focusing on the use of PET and PET/CT in IBD remains still limited; thus, further large multicenter studies will be necessary to substantiate the diagnostic accuracy of these methods in patients with IBD.

Mots-clé
Area Under Curve, Chronic Disease, Confidence Intervals, Fluorodeoxyglucose F18, Humans, Inflammatory Bowel Diseases/diagnostic imaging, Multimodal Imaging, Positron-Emission Tomography, ROC Curve, Radiopharmaceuticals, Tomography, X-Ray Computed
Pubmed
Web of science
Open Access
Oui
Création de la notice
20/08/2017 20:23
Dernière modification de la notice
20/08/2019 14:18
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