Aging and its demographic measurement

Détails

ID Serval
serval:BIB_6192212EE5BD
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Aging and its demographic measurement
Périodique
Nature Education Knowledge
Auteur⸱e⸱s
Bronikowski A.M., Flatt T.
ISSN
sans
Statut éditorial
Publié
Date de publication
2010
Peer-reviewed
Oui
Volume
3
Numéro
10:3
Pages
1-6
Langue
anglais
Notes
Scitable: A collaborative Learning Space for Science
Résumé
This case study highlights the general issues raised earlier. First, that maximum lifespan is not an easily obtainable metric. Specifically, it is unambiguous in the sense that once the last animal dies, it is most definitely dead. But to estimate the variance in maximum lifespan, many replicate populations would need to be followed for each treatment group (with each replicate providing a single observation of maximum lifespan). Second, median lifespan, although measurable from a single population, provides no information on the age-specificity and patterns in age-specific vital rates that are contributing to differences in "aging" (i.e., differences in physiological frailty and rates of increasing mortality across the adult lifespan). Finally, our partitioning of aging into two components - IMR and RoA - allows us to unravel causation in a demographic sense. Specifically, it allows us to specify an aging rate that is separate from its starting value (IMR), independent of fluctuations in survival due to temporary experimental impacts, and not necessarily equivalent to expectations due to median or maximum lifespan.
Création de la notice
28/01/2013 12:50
Dernière modification de la notice
20/08/2019 15:18
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