Bloodstream and endovascular infections due to Abiotrophia defectiva and Granulicatella species.

Détails

Ressource 1Télécharger: BIB_60E04201075E.P001.pdf (282.21 [Ko])
Etat: Public
Version: de l'auteur
ID Serval
serval:BIB_60E04201075E
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Bloodstream and endovascular infections due to Abiotrophia defectiva and Granulicatella species.
Périodique
BMC Infectious Diseases
Auteur(s)
Senn L., Entenza J.M., Greub G., Jaton K., Wenger A., Bille J., Calandra T., Prod'hom G.
ISSN
1471-2334 (Electronic)
ISSN-L
1471-2334
Statut éditorial
Publié
Date de publication
2006
Volume
6
Numéro
9
Pages
1-6
Langue
anglais
Notes
Publication types: Journal Article Publication Status: epublish. PDF type: research article
Résumé
BACKGROUND: Abiotrophia and Granulicatella species, previously referred to as nutritionally variant streptococci (NVS), are significant causative agents of endocarditis and bacteraemia. In this study, we reviewed the clinical manifestations of infections due to A. defectiva and Granulicatella species that occurred at our institution between 1998 and 2004.
METHODS: The analysis included all strains of NVS that were isolated from blood cultures or vascular graft specimens. All strains were identified by 16S rRNA sequence analysis. Patients' medical charts were reviewed for each case of infection.
RESULTS: Eleven strains of NVS were isolated during the 6-year period. Identification of the strains by 16S rRNA showed 2 genogroups: Abiotrophia defectiva (3) and Granulicatella adiacens (6) or "para-adiacens" (2). The three A. defectiva strains were isolated from immunocompetent patients with endovascular infections, whereas 7 of 8 Granulicatella spp. strains were isolated from immunosuppressed patients, mainly febrile neutropenic patients. We report the first case of "G. para-adiacens" bacteraemia in the setting of febrile neutropenia.
CONCLUSION: We propose that Granulicatella spp. be considered as a possible agent of bacteraemia in neutropenic patients.
Mots-clé
Adult, Bacteremia/microbiology, Endocarditis, Bacterial/microbiology, Female, Humans, Infant, Male, Microbial Sensitivity Tests, Middle Aged, Neutropenia/complications, Phylogeny, RNA, Ribosomal, 16S/genetics, Streptococcaceae/classification, Streptococcaceae/genetics
Pubmed
Web of science
Open Access
Oui
Création de la notice
24/01/2008 14:45
Dernière modification de la notice
20/08/2019 15:18
Données d'usage