Experimental endocarditis following dental extractions in rats with periodontitis.

Détails

ID Serval
serval:BIB_5FC9A8ACC131
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Experimental endocarditis following dental extractions in rats with periodontitis.
Périodique
Journal of Oral and Maxillofacial Surgery
Auteur(s)
Overholser C.D., Moreillon P., Glauser M.P.
ISSN
0278-2391 (Print)
ISSN-L
0278-2391
Statut éditorial
Publié
Date de publication
1988
Volume
46
Numéro
10
Pages
857-861
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
This study analyzed the development of bacterial endocarditis following dental extraction in rats with periodontal disease. Periodontal disease was produced in rats by tying silk ligatures around the two maxillary first molars, and placing the animals on a high sucrose diet. Sterile aortic valve vegetations were produced by means of a transaortic catheter, and 24 hours later the maxillary first molars were extracted. The animals were killed 72 hours after the extractions. In rats with periodontal disease induced for 10 and 14 weeks, extractions resulted in an incidence of bacterial endocarditis of 24% and 50%, respectively, most of which were due to streptococcal species (two were caused by Staphylococcus [corrected] aureus). The difference, though not statistically significant (p = 0.10, chi 2 with Yates correction), shows a trend toward increased incidence of endocarditis with increasing severity of periodontal disease. This model demonstrates that one can reliably induce bacterial endocarditis after dental extractions in rats with periodontal disease.
Mots-clé
Animals, Endocarditis, Bacterial/etiology, Endocarditis, Bacterial/microbiology, Female, Periodontitis/microbiology, Rats, Rats, Inbred Strains, Sepsis/etiology, Staphylococcal Infections/microbiology, Streptococcus/isolation & purification, Tooth Extraction/adverse effects
Pubmed
Web of science
Création de la notice
24/01/2008 14:58
Dernière modification de la notice
20/08/2019 15:17
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